SCHEMBL168458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL168457	1.00	MAOB (0.55)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL14938045	0.79	ALDH1A1 (0.45)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL952396	0.78	RELA (0.54)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL5428211	0.78	RELA (0.54)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL3765831	0.78	MAOB (0.50)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL81307	0.78	RELA (0.54)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL5428210	0.78	RELA (0.54)	MAOBRELAALDH1A1LMNANFE2L2
	SCHEMBL13335332	0.78	MAOB (0.50)	MAOBRELAALDH1A1LMNANFE2L2
	(Z)-1,2-Diphenylethene SCHEMBL9134305	0.77	MAOB (0.73)	MAOBRELAALDH1A1LMNANFE2L2
	(Z)-1,2-Diphenylethene SCHEMBL9134296	0.77	MAOB (0.73)	MAOBRELAALDH1A1LMNANFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 850 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.