SCHEMBL16847996

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL827247	0.78	CCR1 (0.48)	MAPTKDM4EALDH1A1NPC1RAB9A
	SCHEMBL16826030	0.75	KDM4E (0.42)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL2160804	0.74	KDM4E (0.54)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL30455909	0.74	KDM4E (0.54)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL474171	0.72	NOTUM (0.61)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL23982542	0.71	RAB9A (0.57)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL16826106	0.71	NOTUM (0.64)	MAPTKDM4EALDH1A1BLMNPC1
	SCHEMBL12501296	0.70	KMO (0.54)	MAPTKDM4EALDH1A1NPC1RAB9A
	SCHEMBL2538923	0.70	CCR1 (0.63)	KDM4EALDH1A1NPC1RAB9AL3MBTL1
	SCHEMBL29633440	0.69	MAPT (0.44)	MAPTKDM4EALDH1A1BLMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.