SCHEMBL1685206

SCHEMBL1685206

CC(C)(C)Cc1cccc(CC(C)(C)C)c1C([NH])=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
RIPK1 Q13546 3/20 0.38
THRB P10828 2/20 0.33
THRA P10827 1/20 0.33
ESR1 P03372 1/20 0.33
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
IAPP P10997 1/20 0.31
CYP2C19 P33261 2/20 0.31
HIF1A Q16665 2/20 0.31
GRN P28799 1/20 0.30
SORT1 Q99523 1/20 0.30
BID P55957 3/20 0.30
MCL1 Q07820 3/20 0.30
BCL2L1 Q07817 2/20 0.30
BAK1 Q16611 2/20 0.30
KAT8 Q9H7Z6 2/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1685282 0.88 CA2 (0.38) GABRA1GABRB2RIPK1TSHRTDP1
SCHEMBL1685284 0.85 GABRA1 (0.37) GABRA1GABRB2MEN1HPGDKMT2A
SCHEMBL1275546 0.80 GABRA1 (0.40) GABRA1GABRB2RIPK1THRBTHRA
SCHEMBL6906894 0.76 FOLH1 (0.44) RIPK1HPGDKMT2ABIDMCL1
SCHEMBL21651081 0.76 BID (0.55) THRBBIDMCL1BCL2L1BAK1
SCHEMBL343948 0.74 FOLH1 (0.43) RIPK1HPGDKMT2AGRNSORT1
SCHEMBL21651053 0.74 RIPK1 (0.38) GABRA1GABRB2RIPK1BIDMCL1
SCHEMBL28863330 0.74 KDM4E (0.37) GABRA1GABRB2RIPK1MEN1HPGD
SCHEMBL1274918 0.73 CA2 (0.38) GABRA1GABRB2RIPK1HPGDKMT2A
SCHEMBL20052279 0.73 THRB (0.37) GABRA1GABRB2RIPK1THRBIAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536907-B Method for producing multipolymer, rubber composition and tire 株式会社普利司通 2022-06-17 CN disclosed
CN-110520449-B Method for producing multipolymer, rubber composition and tire 株式会社普利司通 2021-09-21 CN disclosed
CN-108137759-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2021-03-09 CN disclosed
CN-108137745-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2021-03-09 CN disclosed
CN-108350129-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2021-03-09 CN disclosed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN disclosed
CN-108137758-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2020-10-23 CN disclosed
CN-108137765-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2020-09-18 CN disclosed
CN-108137766-B Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2020-09-04 CN disclosed
CN-108290972-B Polymerization catalyst composition and method for producing conjugated diene polymer 株式会社普利司通 2020-06-26 CN disclosed
US-20050170951-A1 Catalyst composition RIKEN (JP) 2005-08-04 US disclosed
EP-1541593-A1 CATALYST COMPOSITION RIKEN (JP) 2005-06-15 EP disclosed
EP-1500667-A1 CATALYST COMPOSITION Riken (JP) 2005-01-26 EP disclosed
US-6683140-B2 Catalyst for polymerization RIKEN (JP) 2004-01-27 US disclosed
US-20030166458-A1 Block copolymerization of a conjugated diene and an aromatic vinyl compound, which comprises the steps of carrying out homopolymerization of the conjugated diene in the presence of a catalyst composition comprising the following RIKEN (JP) 2003-09-04 US disclosed
US-6596828-B1 polymerization of a conjugated diene or copolymerization of a conjugated diene and an aromatic vinyl compound, which comprises the following components: (A) a metallocene-type complex of a rare earth metal compound (samarium complex RIKEN (JP) 2003-07-22 US disclosed
US-20030018144-A1 Catalyst composition RIKEN (JP) 2003-01-23 US disclosed
EP-1270626-A1 CATALYST COMPOSITION AND PROCESS FOR PRODUCING COPOLYMER Riken (JP) 2003-01-02 EP disclosed
US-20020119889-A1 Catalyst for polymerization RIKEN (JP) 2002-08-29 US disclosed
EP-1086957-A1 CATALYST COMPOSITION Riken (JP) 2001-03-28 EP disclosed