Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | IAPP | P10997 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698123 | 0.76 | LIPG (0.50) | GABRA1GABRB2LIPGRIPK1LIPE | |
| SCHEMBL16576671 | 0.75 | LIPG (0.38) | GABRA1GABRB2LIPGRIPK1LIPE | |
| SCHEMBL20052255 | 0.74 | THRB (0.33) | THRBGABRA1GABRB2 | |
| SCHEMBL1275546 | 0.73 | GABRA1 (0.40) | THRBGABRA1GABRB2RIPK1CYP2C19 | |
| SCHEMBL1685206 | 0.73 | GABRA1 (0.40) | THRBGABRA1GABRB2RIPK1IAPP | |
| SCHEMBL21651053 | 0.71 | RIPK1 (0.38) | GABRA1GABRB2RIPK1 | |
| SCHEMBL3784961 | 0.71 | THRB (0.45) | THRB | |
| SCHEMBL31461653 | 0.69 | THRB (0.43) | THRB | |
| SCHEMBL15698106 | 0.69 | RIPK1 (0.42) | GABRA1GABRB2LIPGRIPK1LIPE | |
| SCHEMBL16576714 | 0.69 | RIPK1 (0.35) | GABRA1GABRB2LIPGRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |