Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303357 | 0.94 | NAAA (0.46) | NAAAPTGS2PTGS1KDM1APTPRC | |
| SCHEMBL16855917 | 0.89 | FGFR2 (0.46) | NAAAPTGS2PTGS1KDM1APTPRC | |
| SCHEMBL16852364 | 0.89 | CCNT1 (0.38) | NAAAKDM4EPOLBHPGDMAPK1 | |
| SCHEMBL16852378 | 0.89 | NAAA (0.43) | NAAAPTGS2PTGS1KDM1APTPRC | |
| SCHEMBL16852421 | 0.89 | CTSL (0.45) | NAAAPTGS2PTGS1KDM1APTPRC | |
| SCHEMBL10303394 | 0.88 | FGFR2 (0.39) | NAAAPTPRCFGFR2FGFR1KDM4E | |
| SCHEMBL16852419 | 0.87 | PPARD (0.41) | CCNT1CDK9CTSLCTSSCTSK | |
| SCHEMBL16852389 | 0.87 | PTGS2 (0.49) | NAAAPTGS2PTGS1KDM4EPOLB | |
| SCHEMBL16852409 | 0.86 | NAAA (0.42) | NAAAPTGS2PTGS1KDM1APTPRC | |
| SCHEMBL16852362 | 0.86 | THRA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |