Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303309 | 0.94 | TDP2 (0.49) | PTGS2LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL16852366 | 0.88 | GABRA1 (0.45) | PTGS2LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL16852377 | 0.87 | NAAA (0.45) | PTGS2LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL16852432 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1PRKCZTDP2CD274 | |
| SCHEMBL16852398 | 0.86 | MGLL (0.46) | PTGS2LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL10303378 | 0.86 | HSD17B1 (0.40) | PTGS2PTGS1 | |
| SCHEMBL16852410 | 0.85 | MGLL (0.46) | PTGS2LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL16852364 | 0.84 | CCNT1 (0.38) | LMNAMAPK1KDM4ENPC1POLB | |
| SCHEMBL15471663 | 0.84 | ALOX5AP (0.40) | LMNAMAPK1KDM4ENPC1POLB | |
| SCHEMBL16856037 | 0.84 | PTGS2 (0.53) | PTGS2LMNAMAPK1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886627-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-05-15 | — | — | EP | disclosed |
| US-9951274-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |