SCHEMBL16857580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12003370	0.87	NPY5R (0.55)	CLK4ALDH1A1HPGDNPC1RAB9A
	SCHEMBL12003356	0.86	NPY5R (0.54)	CLK4ALDH1A1HPGDNPC1RAB9A
	SCHEMBL16864370	0.83	ALDH1A1 (0.49)	ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
	SCHEMBL12003341	0.83	ALDH1A1 (0.48)	ALDH1A1HPGDNPC1RAB9AGRM5
	SCHEMBL12003404	0.83	ALDH1A1 (0.48)	ALDH1A1HPGDNPC1RAB9AGRM5
	SCHEMBL12003459	0.82	PDCD1 (0.49)	ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
	SCHEMBL12018161	0.82	ALDH1A1 (0.55)	ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
	Hydrochloric Acid SCHEMBL15609960	0.81	ALDH1A1 (0.54)	ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
	SCHEMBL27755767	0.81	SLC16A3 (0.48)	SLC16A3DYRK1ACLK4ALDH1A1HPGD
	SCHEMBL12003474	0.81	GRM5 (0.44)	ALDH1A1SMN1; SMN2GRM5LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.