SCHEMBL16864773

SCHEMBL16864773

CC(O)CNN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(C)(C)CO)C3=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ KDM4E B2RXH2 3/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ RECQL P46063 2/20 0.31
▸ TERT O14746 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ RGS12 O14924 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ PABPC1 P11940 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864815 0.86 L3MBTL1 (0.49) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL16864776 0.81 NTRK1 (0.43) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL28084227 0.74 KMT2A (0.46) RAB9AL3MBTL1KDM4EALDH1A1MEN1
SCHEMBL16864828 0.73 RAB9A (0.37) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL16864829 0.73 KMT2A (0.39) NPC1RAB9AL3MBTL1ALDH1A1MEN1
SCHEMBL16864780 0.73 KDM4E (0.43) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL16864784 0.73 KDM4E (0.43) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL16864819 0.71 ALDH1A1 (0.38) NPC1RAB9AL3MBTL1KDM4EALDH1A1
SCHEMBL534520 0.68 ALDH1A1 (0.43) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL16864799 0.66 KCNJ1 (0.37) NPC1RAB9AL3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
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