SCHEMBL16864828

SCHEMBL16864828

CC(O)CNN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(N1CCCCC1)C3=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ TERT O14746 3/20 0.35
▸ ALDH1A1 P00352 6/20 0.34
▸ HTT P42858 1/20 0.34
▸ KMT2A Q03164 4/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ KDM4E B2RXH2 6/20 0.32
▸ HPGD P15428 3/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPT P10636 1/20 0.30
▸ AVPR1A P37288 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ RECQL P46063 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864819 0.88 ALDH1A1 (0.38) RAB9ANPC1L3MBTL1ALDH1A1KMT2A
SCHEMBL16864815 0.85 L3MBTL1 (0.49) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL16864776 0.77 NTRK1 (0.43) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL10100512 0.77 TERT (0.46) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL11948126 0.76 ALDH1A1 (0.41) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL16864773 0.73 NPC1 (0.38) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL28084227 0.73 KMT2A (0.46) RAB9AL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL13780638 0.70 MAPK1 (0.38) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL11948120 0.69 MAPK1 (0.38) RAB9ANPC1L3MBTL1TERTALDH1A1
SCHEMBL11948122 0.69 MAPK1 (0.38) RAB9ANPC1L3MBTL1TERTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
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