SCHEMBL16864829

SCHEMBL16864829

CC(O)CNN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1CO)C3=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.39
▸ MEN1 O00255 5/20 0.39
▸ USP2 O75604 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ CRHBP P24387 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ BRCA1 P38398 1/20 0.39
▸ CASP7 P55210 1/20 0.39
▸ HBB P68871 1/20 0.39
▸ CRHR2 Q13324 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ NR1H3 Q13133 4/20 0.37
▸ NR1H2 P55055 4/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ PDCD1 Q15116 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16864815 0.82 L3MBTL1 (0.49) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL16417481 0.82 NR1H2 (0.50) KMT2AMEN1USP2ALDH1A1GAA
SCHEMBL16864776 0.77 NTRK1 (0.43) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL28084227 0.76 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTL3MBTL1
SCHEMBL16866480 0.75 NR1H3 (0.38) KMT2AMEN1USP2ALDH1A1GAA
SCHEMBL12556946 0.75 ANPEP (0.55) KMT2AMEN1USP2ALDH1A1GAA
SCHEMBL16864773 0.73 NPC1 (0.38) KMT2AMEN1ALDH1A1GAAL3MBTL1
SCHEMBL16601811 0.71 ANPEP (0.50) KMT2AMEN1USP2ALDH1A1GAA
SCHEMBL16601691 0.70 NR1H3 (0.55) KMT2AMEN1USP2ALDH1A1GAA
SCHEMBL16864828 0.69 RAB9A (0.37) KMT2AMEN1ALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-9335645-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-05-10 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
US-20150185633-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-07-02 — — US disclosed
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