SCHEMBL16865693

SCHEMBL16865693

O=S1(=O)CCOCN1CN1COCCS1(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19292918 0.77
SCHEMBL16868384 0.76 ADRA2B (0.59)
SCHEMBL16865696 0.73
SCHEMBL16865695 0.72 MEN1 (0.50) MEN1POLBKMT2A
SCHEMBL18195192 0.62 ALDH1A1 (0.35) MEN1POLBKMT2A
SCHEMBL24568398 0.58 SMN1; SMN2 (0.32)
SCHEMBL14514785 0.57
SCHEMBL18591636 0.57
SCHEMBL256062 0.55
SCHEMBL5539788 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159477-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS GEISTLICH PHARMA AG (CH) 2023-05-25 US disclosed
US-20230159477-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS GEISTLICH PHARMA AG (CH) 2023-05-25 US disclosed
EP-4011871-A2 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS Geistlich Pharma AG (CH) 2022-06-15 EP disclosed
EP-3233813-B1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS GEISTLICH PHARMA AG (CH) 2022-02-02 EP disclosed
US-20210163432-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS GEISTLICH PHARMA AG (CH) 2021-06-03 US disclosed
US-10968190-B2 Processes for preparing oxathiazin-like compounds GEISTLICH PHARMA AG (CH) 2021-04-06 US disclosed
US-10736902-B2 Method of treating triple negative breast cancer GEISTLICH PHARMA AG (CH) 2020-08-11 US disclosed
US-10392355-B2 Processes for preparing oxathiazin-like compounds GEISTLICH PHARMA AG (CH) 2019-08-27 US disclosed
US-20190091233-A1 METHOD OF TREATING TRIPLE NEGATIVE BREAST CANCER GEISTLICH PHARMA AG (CH) 2019-03-28 US disclosed
US-9844555-B2 Oxathiazine derivatives as antibacterial and anticancer agents GEISTLICH PHARMA AG (CH) 2017-12-19 US disclosed
US-20170196876-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS GEISTLICH PHARMA AG (CH) 2017-07-13 US disclosed
US-9624187-B2 Oxathiazine derivatives as antibacterial and anticancer agents GEISTLICH PHARMA AG (CH) 2017-04-18 US disclosed
US-9624187-B2 Oxathiazine derivatives as antibacterial and anticancer agents GEISTLICH PHARMA AG (CH) 2017-04-18 US disclosed
WO-2016098054-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS GEISTLICH PHARMA AG (CH) 2016-06-23 WO disclosed
US-20160159759-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS GEISTLICH PHARMA AG (CH) 2016-06-09 US disclosed
US-20160159759-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS GEISTLICH PHARMA AG (CH) 2016-06-09 US disclosed
US-9241943-B2 Oxathiazine derivatives as antibacterial and anticancer agents GEISTLICH PHARMA AG (CH) 2016-01-26 US disclosed
US-9241943-B2 Oxathiazine derivatives as antibacterial and anticancer agents GEISTLICH PHARMA AG (CH) 2016-01-26 US disclosed
US-20150182534-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS GEISTLICH PHARMA AG (CH) 2015-07-02 US disclosed
US-20150182534-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS GEISTLICH PHARMA AG (CH) 2015-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10736902-B2 Method of treating triple negative breast cancer IL2, TTBK2, TOP2A MEN1 3955/4885POLB 1469/4885KMT2A 624/4885
US-20150182534-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS OXA1L, TOP2A, HELZ MEN1 3082/4885POLB 1312/4885KMT2A 1998/4885
US-20230159477-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS OXA1L, MAPT, OTC MEN1 1059/4885POLB 110/4885KMT2A 3018/4885
US-10392355-B2 Processes for preparing oxathiazin-like compounds OXA1L, MAPT, OTC MEN1 1059/4885POLB 110/4885KMT2A 3018/4885
US-10968190-B2 Processes for preparing oxathiazin-like compounds DCXR, SORD, ADH1C MEN1 4659/4885POLB 916/4885KMT2A 4252/4885
US-20170196876-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS TOP2A, OXA1L, TOP1 MEN1 3155/4885POLB 580/4885KMT2A 2479/4885
US-20210163432-A1 PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS OXA1L, MAPT, OTC MEN1 1059/4885POLB 110/4885KMT2A 3018/4885
US-20160159759-A1 OXATHIAZINE DERIVATIVES AS ANTIBACTERIAL AND ANTICANCER AGENTS TOP2A, OXA1L, TOP1 MEN1 3155/4885POLB 580/4885KMT2A 2479/4885
US-20190091233-A1 METHOD OF TREATING TRIPLE NEGATIVE BREAST CANCER IL2, TTBK2, TOP2A MEN1 3955/4885POLB 1469/4885KMT2A 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.