SCHEMBL168718

SCHEMBL168718

C=CCNc1[c]cccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
RAB9A P51151 3/20 0.38
LMNA P02545 3/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
GAA P10253 2/20 0.38
MITF O75030 1/20 0.38
NSD2 O96028 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SLC2A1 P11166 1/20 0.36
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4217147 0.80
SCHEMBL5480767 0.72
SCHEMBL343994 0.72
SCHEMBL5472820 0.72
SCHEMBL4599615 0.72 LMNA (0.36) ALDH1A1KMT2ALMNAHPGDMEN1
SCHEMBL4598425 0.72 HPGD (0.37) ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A
SCHEMBL4600271 0.72 LMNA (0.42) ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A
SCHEMBL5538617 0.71 SLC2A1 (0.39) ALDH1A1KDM4EKMT2ASMN1; SMN2RAB9A
SCHEMBL8152713 0.71 MAOA (0.33)
SCHEMBL4760595 0.69 HDAC3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 US claimed
CN-115612000-A Infrared light sensitive photo-curing composition 保定乐凯新材料股份有限公司 2023-01-17 CN claimed
CN-108351587-B Resist composition 曼彻斯特大学 2022-08-19 CN claimed
US-20210346321-A1 PHARMACEUTICAL COMPOSITION CONTAINING ALKYL CARBAMOYL NAPHTHALENYLOXY OCTENOYL HYDROXYAMIDE PHOSPHATE, TARTRATE OR COMBINATION THEREOF, AND PREPARATION METHOD THEREFOR CRYSTALGENOMICS, INC. (KR) 2021-11-11 US claimed
EP-3875081-A1 PHARMACEUTICAL COMPOSITION CONTAINING ALKYL CARBAMOYL NAPHTHALENYLOXY OCTENOYL HYDROXYAMIDE PHOSPHATE, TARTRATE OR COMBINATION THEREOF, AND PREPARATION METHOD THEREFOR Crystalgenomics, Inc. (KR) 2021-09-08 EP claimed
CN-113024341-A Method for regio-and stereoselectively synthesizing (E, E) -1,4, 4-trisubstituted conjugated diene 温州大学 2021-06-25 CN claimed
CN-113024342-A Method for regio-and stereoselectively synthesizing (E) -2,4, 4-trisubstituted conjugated diene 温州大学 2021-06-25 CN claimed
EP-3777847-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF FIBROSIS Crystalgenomics, Inc. (KR) 2021-02-17 EP claimed
US-20210015772-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF FIBROSIS CRYSTALGENOMICS, INC. (KR) 2021-01-21 US claimed
US-20200283371-A1 PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYLHYDROXYAMIDE OR OF DERIVATIVE THEREOF AND METHOD FOR PREPARING SAME CRYSTALGENOMICS, INC. (KR) 2020-09-10 US claimed
EP-0231622-A2 Inhibition of the 5-lipoxygenase pathway SMITHKLINE BEECHAM CORPORATION (US) 1987-08-12 EP claimed
CN-86108538-A The inhibition of 5-lipoxygenase pathway 1987-07-29 CN claimed
EP-0184384-A1 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them PFIZER INC. (US) 1986-06-11 EP claimed
EP-0135711-A1 5-thioxo-2-imidazolinyl benzoic acids, esters, salts and related compounds, and use thereof as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1985-04-03 EP claimed
EP-0133309-A1 Herbicides and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1985-02-20 EP claimed
US-4355823-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1982-10-26 US claimed
US-4331676-A 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION CIBA-GEIGY CORPORATION (US) 1982-05-25 US claimed
US-4192868-A ANTIINFLAMMATORY, ANALGESIC CIBA-GEIGY CORPORATION (US) 1980-03-11 US claimed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US claimed
US-3996253-A 2-UREIDO-PHENOLS AS COLOR COUPLERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-12-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210346321-A1 PHARMACEUTICAL COMPOSITION CONTAINING ALKYL CARBAMOYL NAPHTHALENYLOXY OCTENOYL HYDROXYAMIDE PHOSPHATE, TARTRATE OR COMBINATION THEREOF, AND PREPARATION METHOD THEREFOR AGPAT5, NOTUM, HADH ALDH1A1 3493/4885KDM4E 2720/4885KMT2A 2545/4885
US-20200283371-A1 PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYLHYDROXYAMIDE OR OF DERIVATIVE THEREOF AND METHOD FOR PREPARING SAME DOHH, CYP51A1, CYP46A1 ALDH1A1 690/4885KDM4E 333/4885KMT2A 397/4885
US-20210015772-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF FIBROSIS FIBP, MMP1, CFTR ALDH1A1 761/4885KDM4E 1709/4885KMT2A 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.