Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | DGKA | P23743 | 2/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260200 | 1.00 | TSHR (0.62) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL16874358 | 0.98 | TSHR (0.66) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL16874344 | 0.98 | TSHR (0.66) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL16874336 | 0.98 | TSHR (0.66) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL31538276 | 0.93 | TSHR (0.60) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL22832725 | 0.93 | TSHR (0.60) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL22832724 | 0.93 | TSHR (0.60) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL8744230 | 0.88 | TSHR (0.60) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL8744225 | 0.88 | TSHR (0.60) | TSHRDGKAPAMALDH1A1CYP3A4 | |
| SCHEMBL830241 | 0.87 | TSHR (0.61) | TSHRDGKAPAMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-11332694-B2 | Pyrrole compound, method of making same, and aroma composition, food, drink and cosmetics containing same | T. HASEGAWA CO., LTD. (JP) | 2022-05-17 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10695277-B2 | Pro-fragrance composition | AQDOT LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-20200157463-A1 | PYRROLE COMPOUND, AROMA COMPOSITION, AND FOOD AND DRINK AND COSMETICS CONTAINING THE SAME | T. HASEGAWA CO., LTD. (JP) | 2020-05-21 | — | — | US | disclosed |
| US-20190046426-A1 | PRO-FRAGRANCE COMPOSITION | AQDOT LIMITED (GB) | 2019-02-14 | — | — | US | disclosed |
| EP-3416729-A1 | PRO-FRAGRANCE COMPOSITION | Aqdot Limited (GB) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017141030-A1 | PRO-FRAGRANCE COMPOSITION | AQDOT LIMITED (GB) | 2017-08-24 | — | — | WO | disclosed |
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | TSHR 3246/4885DGKA 1682/4885PAM 3654/4885 |
| US-20200157463-A1 | PYRROLE COMPOUND, AROMA COMPOSITION, AND FOOD AND DRINK AND COSMETICS CONTAINING THE SAME | TAS1R1, TAS2R1, TAS1R2 | TSHR 1423/4885DGKA 2936/4885PAM 1926/4885 |
| US-20190046426-A1 | PRO-FRAGRANCE COMPOSITION | COPS5, COPS8, CBR3 | TSHR 4423/4885DGKA 3100/4885PAM 2385/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | TSHR 3246/4885DGKA 1682/4885PAM 3654/4885 |
| US-11332694-B2 | Pyrrole compound, method of making same, and aroma composition, food, drink and cosmetics containing same | TAS2R1, TAS1R1, TAS2R10 | TSHR 1742/4885DGKA 2259/4885PAM 1249/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | TSHR 3246/4885DGKA 1682/4885PAM 3654/4885 |
| US-10695277-B2 | Pro-fragrance composition | COPS5, COPS8, CBR3 | TSHR 4423/4885DGKA 3100/4885PAM 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.