SCHEMBL1689493

SCHEMBL1689493

CC1=NN(c2ccccc2)C(=O)C1N=Nc1ccc(C)cc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.70
▸ ALDH1A1 P00352 9/20 0.70
▸ SMN1; SMN2 Q16637 5/20 0.70
▸ NPC1 O15118 4/20 0.70
▸ RAB9A P51151 4/20 0.70
▸ MAPK1 P28482 4/20 0.70
▸ TDP1 Q9NUW8 3/20 0.70
▸ LMNA P02545 2/20 0.70
▸ MEN1 O00255 11/20 0.62
▸ KMT2A Q03164 11/20 0.62
▸ L3MBTL1 Q9Y468 2/20 0.62
▸ POLB P06746 2/20 0.62
▸ KDM4E B2RXH2 1/20 0.62
▸ ATM Q13315 2/20 0.60
▸ GAA P10253 3/20 0.58
▸ CYP1A2 P05177 2/20 0.58
▸ CYP2C9 P11712 2/20 0.55
▸ CYP2D6 P10635 1/20 0.55
▸ LOX P28300 1/20 0.50
▸ LOXL3 P58215 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1689492 1.00 MAPT (0.70) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL1689490 1.00 MAPT (0.70) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL21436723 0.85 MAPT (0.60) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL16645429 0.84 MAPT (0.81) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL2641828 0.83 MAPT (0.64) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL30078720 0.83 MAPT (0.64) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL29350167 0.83 MAPT (0.64) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL2641824 0.83 MAPT (0.64) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL305974 0.82 MAPT (1.00) MAPTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL305975 0.82 MAPT (1.00) MAPTALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503528-B2 Thermoplastic moulding composition with improved weathering resistance RÖHM GMBH (DE) 2025-12-23 — — US claimed
CN-119805862-A Colored photosensitive resin composition, color filter, developing device and preparation method 阜阳欣奕华新材料科技股份有限公司 2025-04-11 — — CN claimed
EP-4165118-B1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE ROEHM GMBH (DE) 2024-11-06 — — EP claimed
US-20230212333-A1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE RÖHM GMBH (DE) 2023-07-06 — — US claimed
US-20230203313-A1 PROCESS FOR COLOURING A THERMOPLASTIC POLYMER RÖHM GMBH (DE) 2023-06-29 — — US claimed
EP-4165123-A1 PROCESS FOR COLOURING A THERMOPLASTIC POLYMER Röhm GmbH (DE) 2023-04-19 — — EP claimed
EP-4165118-A1 THERMOPLASTIC MOULDING COMPOSITION WITH IMPROVED WEATHERING RESISTANCE Röhm GmbH (DE) 2023-04-19 — — EP claimed
CN-115698156-A Method for coloring thermoplastic polymers 罗姆化学有限责任公司 2023-02-03 — — CN claimed
JP-2010508092-A — — 2010-03-18 — — JP claimed
EP-2077900-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY, Yichieh (US) 2009-07-15 — — EP claimed
WO-2008103754-A2 AESTHETIC INTRAOCULAR IMPLANT TSENG JANET C (US) 2008-08-28 — — WO claimed
WO-2008055118-A2 METHODS AND SYSTEMS FOR IMMOBILIZING CORNEAL PROSTHESES SHIUEY YICHIEH (US) 2008-05-08 — — WO claimed
US-12629345-B2 Methods, compositions, and devices for drug / live cell microarrays PATHAK HOLDINGS LLC (US) 2026-05-19 — — US disclosed
US-20260097181-A1 GRADIENT ANNEALING OF POLYMERIC COMPONENTS Access Vascular, Inc. (US) 2026-04-09 — — US disclosed
US-20260035579-A1 RYLENE-BASED UV CURABLE SECURITY INK COMPOSITIONS SICPA HOLDING SA (CH) 2026-02-05 — — US disclosed
WO-2025264839-A1 GRADIENT ANNEALING OF POLYMERIC COMPONENTS Access Vascular, Inc. (US) 2025-12-26 — — WO disclosed
EP-0972223-A1 LIGHT FILTERING CONTACT LENS PARAGON VISION SCIENCES, INC. (US) 2000-01-19 — — EP disclosed
US-5846457-A Light filtering contact lens method SPORTSIGHT, LLC 1998-12-08 — — US disclosed
WO-1998044380-A1 LIGHT FILTERING CONTACT LENS PARAGON VISION SCIENCES, INC. (US) 1998-10-08 — — WO disclosed
US-5617154-A Light filtering contact lens FLEXLENS (US) 1997-04-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629345-B2 Methods, compositions, and devices for drug / live cell microarrays SRMS, FKBP4, MYL4 MAPT 1283/4885ALDH1A1 2168/4885SMN1; SMN2 4455/4885
US-20260097181-A1 GRADIENT ANNEALING OF POLYMERIC COMPONENTS AQP3, AQP1, ELOC MAPT 595/4885ALDH1A1 4582/4885SMN1; SMN2 218/4885
US-20260035579-A1 RYLENE-BASED UV CURABLE SECURITY INK COMPOSITIONS RB1, CDK1, MARK1 MAPT 2133/4885ALDH1A1 1951/4885SMN1; SMN2 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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