Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011632 | 0.81 | TSHR (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL25132526 | 0.79 | TYR (0.32) | — | |
| SCHEMBL18732234 | 0.79 | NPC1 (0.30) | — | |
| SCHEMBL15723894 | 0.79 | LMNA (0.33) | DAO | |
| SCHEMBL18433896 | 0.77 | NOS3 (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15473482 | 0.74 | NPC1 (0.37) | — | |
| SCHEMBL14256849 | 0.73 | TSHR (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1275292 | 0.73 | TSHR (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10138706 | 0.73 | NOS1 (0.41) | — | |
| SCHEMBL25748026 | 0.73 | TP53 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714654-B1 | 4-Aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group | BAYER IP GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |