Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16918931 | 0.79 | HTR3E (0.32) | — | |
| SCHEMBL19884769 | 0.79 | PTGS2 (0.36) | HSP90AB1ACHE | |
| SCHEMBL15723894 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL18732234 | 0.78 | NPC1 (0.30) | NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL18433896 | 0.75 | NOS3 (0.37) | — | |
| SCHEMBL19826377 | 0.75 | ACHE (0.34) | HSP90AB1ACHE | |
| SCHEMBL18458575 | 0.72 | ALDH1A1 (0.50) | TYRHSP90AB1ACHENPC1LMNA | |
| SCHEMBL14327172 | 0.72 | BACE1 (0.41) | — | |
| SCHEMBL13325401 | 0.72 | BACE1 (0.50) | ACHELMNA | |
| SCHEMBL10138706 | 0.72 | NOS1 (0.41) | NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057812-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |