Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593772 | 0.95 | LMNA (0.63) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL28793573 | 0.93 | LMNA (0.61) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL14707645 | 0.91 | LMNA (0.55) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL2010436 | 0.89 | LMNA (0.59) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL17188986 | 0.89 | LMNA (0.53) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL10149317 | 0.88 | LMNA (0.52) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL6749439 | 0.87 | LMNA (0.55) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL10149312 | 0.86 | LMNA (0.69) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL16957540 | 0.86 | LMNA (0.50) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL16950528 | 0.86 | LMNA (0.55) | LMNAMAPTKDM4ECYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193789-B1 | The application of 3,5-dihydroxytoluene or derivatives thereof in the preparation of medicine and functional food for treating or preventing depression | KUNMING INST BOTANY CN ACAD (CN) | 2013-02-20 | — | — | EP | claimed |
| US-20100190730-A1 | APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2010-07-29 | — | — | US | claimed |
| EP-2193789-A1 | THE APPLICATION OF 3, 5-DIHYDROXYTOLUENE OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINE AND FUNCTIONAL FOR TREATING OR PREVENTING DEPRESSION. | Kunming Institute Of Botany, Chinese Academy Of Sciences (CN) | 2010-06-09 | — | — | EP | claimed |
| WO-2023187302-A1 | NOVEL PLASTICIZERS, PROCESS FOR THE PREPARATION THEREOF, AND USE THEREOF | ORPIA INNOVATION (FR) | 2023-10-05 | — | — | WO | disclosed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-11136343-B2 | Binuclear metal complexes for use as emitters in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-10-05 | — | — | US | disclosed |
| US-20200360379-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | GLAXOSMITHKLINE S.P.A. (IT) | 2020-11-19 | — | — | US | disclosed |
| EP-2193789-A1 | THE APPLICATION OF 3, 5-DIHYDROXYTOLUENE OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINE AND FUNCTIONAL FOR TREATING OR PREVENTING DEPRESSION. | Kunming Institute Of Botany, Chinese Academy Of Sciences (CN) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193789-A1 | THE APPLICATION OF 3, 5-DIHYDROXYTOLUENE OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINE AND FUNCTIONAL FOR TREATING OR PREVENTING DEPRESSION. | Kunming Institute Of Botany, Chinese Academy Of Sciences (CN) | 2010-06-09 | — | — | EP | disclosed |
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| US-7323458-B1 | Dihydrobenzodiazepins and their use for treating dyslipidemia | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-29 | — | — | US | disclosed |
| US-7323458-B1 | Dihydrobenzodiazepins and their use for treating dyslipidemia | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-29 | — | — | US | disclosed |
| EP-1663234-A1 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF HIV INFECTIONS | Pfizer Limited (GB) | 2006-06-07 | — | — | EP | disclosed |
| US-20050043300-A1 | Piperazine derivatives | PFIZER INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2005016344-A1 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF HIV INFECTIONS | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | LMNA 1917/4885MAPT 3926/4885KDM4E 1460/4885 |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNN3, KCND3, KCNA3 | LMNA 1917/4885MAPT 3926/4885KDM4E 1460/4885 |
| US-20200360379-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNN3, KCND3, KCNA3 | LMNA 1917/4885MAPT 3926/4885KDM4E 1460/4885 |
| US-20050043300-A1 | Piperazine derivatives | CD4, CCR5, RRP15 | LMNA 3961/4885MAPT 2428/4885KDM4E 2439/4885 |
| US-11136343-B2 | Binuclear metal complexes for use as emitters in organic electroluminescent devices | AP2M1, MCU, AP3M1 | LMNA 3190/4885MAPT 1256/4885KDM4E 4613/4885 |
| US-20100190730-A1 | APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION | TPH1, TPH2, HTR5A | LMNA 597/4885MAPT 3939/4885KDM4E 143/4885 |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | LMNA 1917/4885MAPT 3926/4885KDM4E 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.