Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955754 | 0.86 | GABRA1 (0.46) | GABRA1GABRB2ACHECYP2C19KDM4E | |
| SCHEMBL16956054 | 0.84 | CES2 (0.38) | — | |
| SCHEMBL16950836 | 0.84 | ACHE (0.40) | GABRA1GABRB2HMGCRACHECYP2C19 | |
| SCHEMBL16959690 | 0.82 | TTR (0.36) | GABRA1GABRB2 | |
| SCHEMBL16959474 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2HMGCRACHECYP2C19 | |
| SCHEMBL16958822 | 0.79 | RXRA (0.40) | GABRA1GABRB2ACHECYP2C19MAPT | |
| SCHEMBL16956521 | 0.78 | NOTUM (0.37) | GABRA1GABRB2ACHECYP2C19HTR1D | |
| SCHEMBL16962958 | 0.78 | ACHE (0.35) | GABRA1GABRB2ACHECYP2C19HTR1D | |
| SCHEMBL16956767 | 0.76 | HSPA5 (0.35) | GABRA1GABRB2ACHECYP2C19 | |
| SCHEMBL16961626 | 0.75 | CYP1A2 (0.33) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |