Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955754 | 0.86 | GABRA1 (0.46) | ACHEGABRA1GABRB2PTPN7DUSP3 | |
| SCHEMBL16961873 | 0.85 | ACHE (0.41) | ACHEGABRA1GABRB2PTPN7DUSP3 | |
| SCHEMBL16950849 | 0.85 | CES2 (0.39) | DDR1CES2 | |
| SCHEMBL16958822 | 0.79 | RXRA (0.40) | ACHEGABRA1GABRB2CYP2C19HTR1D | |
| SCHEMBL16956521 | 0.78 | NOTUM (0.37) | ACHEGABRA1GABRB2PTPN7DUSP3 | |
| SCHEMBL16953013 | 0.78 | GABRA1 (0.34) | ACHEGABRA1GABRB2CYP2C19HTR1D | |
| SCHEMBL31072829 | 0.77 | ACHE (0.44) | ACHEGABRA1GABRB2SLC6A3CES2 | |
| SCHEMBL16956767 | 0.76 | HSPA5 (0.35) | ACHEGABRA1GABRB2PTPN7DUSP3 | |
| SCHEMBL16961626 | 0.75 | CYP1A2 (0.33) | GABRA1GABRB2 | |
| SCHEMBL16955876 | 0.75 | CA1 (0.39) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |