SCHEMBL16953897

SCHEMBL16953897

C#Cc1c(C)cccc1[CH]O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
TSHR P16473 1/20 0.34
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
TRPA1 O75762 2/20 0.31
ATM Q13315 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2A6 P11509 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
MPI P34949 1/20 0.31
RECQL P46063 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP2C19 P33261 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16951995 0.80 CYP1A2 (0.46) ALDH1A1TSHRTRPA1ATMCYP1A2
SCHEMBL1249412 0.78 CYP1A2 (0.43) ALDH1A1TSHRGABRA1GABRB2TRPA1
SCHEMBL16962282 0.78 TRPA1 (0.37) ALDH1A1TSHRTRPA1CYP1A2CYP2A6
SCHEMBL16952399 0.78 ERN1 (0.38) ALDH1A1TSHRTRPA1KDM4EPOLB
SCHEMBL16959528 0.77 ALOX12 (0.42) ALDH1A1TSHRGABRA1GABRB2CA2
SCHEMBL16956042 0.77 ALOX5 (0.33) ALDH1A1MAPT
SCHEMBL16960633 0.76 ERN1 (0.38)
SCHEMBL16959339 0.76 HSD11B1 (0.33)
SCHEMBL16953140 0.76
SCHEMBL16955561 0.76 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed