SCHEMBL1249412

SCHEMBL1249412

C#Cc1c(C)cccc1C

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
CYP2A6 P11509 2/20 0.43
ACHE P22303 3/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 4/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CYP2C19 P33261 1/20 0.39
TRPA1 O75762 2/20 0.36
CD44 P16070 1/20 0.36
ATM Q13315 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.32
FFAR1 O14842 1/20 0.32
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4948998 0.85 TSHR (0.39) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL1459645 0.83 ACHE (0.48) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL3220920 0.83 CYP1A2 (0.35) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL6941036 0.81 GABRA1 (0.52) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL8420785 0.79 CYP1A2 (0.41) CYP1A2CYP2A6TSHRALDH1A1CA1
SCHEMBL16956053 0.79 TSHR (0.35) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL16955373 0.79 ALDH1A1 (0.36) CYP1A2CYP2A6ACHETSHRALDH1A1
SCHEMBL16953897 0.78 ALDH1A1 (0.34) CYP1A2CYP2A6TSHRALDH1A1CA1
SCHEMBL31168897 0.76 ALDH1A1 (0.55) CYP1A2TSHRALDH1A1CA1CA2
SCHEMBL1713099 0.76 ALDH1A1 (0.55) CYP1A2TSHRALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401999-B Process for preparing high sulfur content copolymers 艾尼股份公司 2023-11-14 CN claimed
US-20220267487-A1 PROCESS FOR HIGH SULFER CONTENT COPOLYMER PREPARATION ENI S.P.A. (IT) 2022-08-25 US claimed
EP-3997134-A1 PROCESS FOR HIGH SULFUR CONTENT COPOLYMER PREPARATION ENI S.p.A. (IT) 2022-05-18 EP claimed
CN-114401999-A Process for preparing high sulfur content copolymers 艾尼股份公司 2022-04-26 CN claimed
WO-2021005511-A1 PROCESS FOR HIGH SULFUR CONTENT COPOLYMER PREPARATION ENI S.P.A. (IT) 2021-01-14 WO claimed
US-20250066377-A1 AMINO CHROMEN-2-ONE MODULATORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2025-02-27 US disclosed
CN-114401999-B Process for preparing high sulfur content copolymers 艾尼股份公司 2023-11-14 CN disclosed
WO-2023114539-A1 AMINO CHROMEN-2-ONE MODULATORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed
CN-112358459-B Preparation method of benzofuran compound 心远(广州)药物研究有限公司 2023-01-17 CN disclosed
US-20220267487-A1 PROCESS FOR HIGH SULFER CONTENT COPOLYMER PREPARATION ENI S.P.A. (IT) 2022-08-25 US disclosed
EP-3997134-A1 PROCESS FOR HIGH SULFUR CONTENT COPOLYMER PREPARATION ENI S.p.A. (IT) 2022-05-18 EP disclosed
CN-114401999-A Process for preparing high sulfur content copolymers 艾尼股份公司 2022-04-26 CN disclosed
WO-2011036130-A1 INDOLE DERIVATIVES AS CRAC MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2011-03-31 WO disclosed
US-20110071150-A1 INDOLE DERIVATIVES AS CRAC MODULATORS ALAM MUZAFFAR 2011-03-24 US disclosed
US-20110046133-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2011-02-24 US disclosed
EP-2074089-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2009-07-01 EP disclosed
WO-2008048991-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2008-04-24 WO disclosed
US-6458967-B1 REACTING ACETYLENE COMPOUNDS TO FORM ENOL ETHER; REACTING WITH SULFUR OR SELENIUM OR TELLURIUM COMPOUND TO FORM DYE PRODUCT THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2002-10-01 US disclosed
US-20020022723-A1 Method for preparation of an intermediate dye product RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE STATE UNIVERSITY OF NEW YORK AT BUFFALO 2002-02-21 US disclosed
WO-2002000642-A1 METHOD FOR PREPARATION OF AN INTERMEDIATE DYE PRODUCT THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071150-A1 INDOLE DERIVATIVES AS CRAC MODULATORS ORAI1, RYR2, CACNA1E CYP1A2 1233/4885CYP2A6 1523/4885ACHE 666/4885
US-20020022723-A1 Method for preparation of an intermediate dye product SRD5A1, SRD5A2, RER1 CYP1A2 120/4885CYP2A6 1241/4885ACHE 1380/4885
US-20250066377-A1 AMINO CHROMEN-2-ONE MODULATORS OF POLRMT POLRMT, TFAM, POLM CYP1A2 1811/4885CYP2A6 3548/4885ACHE 4193/4885
US-20110046133-A1 ORGANIC COMPOUNDS DGAT1, DGAT2, SOAT1 CYP1A2 1025/4885CYP2A6 1352/4885ACHE 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.