Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952648 | 0.85 | THRB (0.35) | ALDH1A1F2RLMNASMN1; SMN2THRB | |
| SCHEMBL16953918 | 0.83 | L3MBTL1 (0.38) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL16960803 | 0.83 | THRB (0.38) | ALDH1A1F2RLMNASMN1; SMN2THRB | |
| SCHEMBL16958505 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL16959311 | 0.82 | HCRTR1 (0.41) | ALDH1A1LMNAGAAKMT2AMAPT | |
| SCHEMBL16956756 | 0.81 | LMNA (0.33) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL16953320 | 0.81 | GABRA1 (0.37) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL16950579 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL16955894 | 0.78 | ELANE (0.35) | ALDH1A1LMNAKMT2ATSHRATM | |
| SCHEMBL16952216 | 0.77 | HPGD (0.40) | ALDH1A1LMNASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |