Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960011 | 0.85 | EDNRB (0.36) | EDNRBEDNRAGABRA1PYCR1LMNA | |
| SCHEMBL25908131 | 0.84 | GABRA1 (0.43) | EDNRBEDNRAGABRA1GABRB2PYCR1 | |
| SCHEMBL16952684 | 0.81 | GABRA1 (0.32) | EDNRBEDNRAGABRA1GABRB2PYCR1 | |
| SCHEMBL16956297 | 0.80 | L3MBTL1 (0.33) | GABRA1GABRB2PYCR1HPGDLMNA | |
| SCHEMBL16954881 | 0.80 | PYCR1 (0.33) | EDNRBEDNRAGABRA1GABRB2PYCR1 | |
| SCHEMBL16953099 | 0.78 | TRPA1 (0.35) | LMNAL3MBTL1MAPTRXFP1 | |
| SCHEMBL16959886 | 0.78 | ALDH1A1 (0.40) | EDNRBEDNRALMNASMN1; SMN2TSHR | |
| SCHEMBL16951787 | 0.77 | LMNA (0.37) | LMNATSHRL3MBTL1NPSR1MAPT | |
| SCHEMBL16950445 | 0.77 | PSEN1 (0.35) | LMNASMN1; SMN2MAPT | |
| SCHEMBL16960772 | 0.77 | CYP2A6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |