Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671296 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| Phosphine SCHEMBL27638416 | 0.80 | CCR1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL30738240 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL29993166 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL169378 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL29354893 | 0.77 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL69979 | 0.77 | CRHBP (0.37) | KMT2ATDP1CYP3A4TSHR | |
| SCHEMBL8193 | 0.77 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28304525 | 0.77 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL1089189 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620946-B | Preparation method of 2-chloro-1, 8-naphthyridine derivatives | 山东明化新材料有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-113620946-A | Preparation method of 2-chloro-1, 8-naphthyridine derivatives | 山东明化新材料有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-108239099-A | Compound and its preparation method and application | 中国科学院上海高等研究院 | 2018-07-03 | — | — | CN | claimed |
| CN-105061421-A | Method for preparing 2-chloro-1, 8-naphthyridine derivative | UNIV CHINA PETROLEUM | 2015-11-18 | — | — | CN | claimed |
| US-12522595-B2 | Bicyclic ether O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2026-01-13 | — | — | US | disclosed |
| CN-119118872-A | Tetrahydronaphthalene and tetrahydroquinoline compounds as HIF-2 alpha inhibitors | 艾库斯生物科学有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117820371-A | Method for esterification of azanaphthalene ring-C2-thiophosphoric acid | 湖南科技学院 | 2024-04-05 | — | — | CN | disclosed |
| EP-4272824-A2 | SUBSTITUTED 2-AZABICYCLES AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3622956-B9 | SUBSTITUTED 2-AZABICYCLES AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-09-27 | — | — | EP | disclosed |
| CN-112110920-B | Organic electroluminescent compound and application thereof | 北京鼎材科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-3622956-B1 | SUBSTITUTED 2-AZABICYCLES AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |
| CN-115968286-A | Heteroaryl compounds, their preparation and use | 益方生物科技(上海)股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-5258528-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009596-A1 | INDIVIDUAL STEREOISOMERS OF 7-[3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4536208-A | Certain naphthyridine diether compounds and their herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| US-4533381-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4472193-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |