SCHEMBL1697442

SCHEMBL1697442

C=C(c1ccc2c(c1)c(C(C)C1CCCN1)cn2C(C)=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HTR6 P50406 3/20 0.33
CREBBP Q92793 7/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697469 0.79 HTR6 (0.38) SLC6A2SLC6A4SLC6A3HTR6POLB
SCHEMBL1697462 0.77 PRPS1 (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL6968879 0.73 DYRK1A (0.42) SLC6A2SLC6A4SLC6A3HTR6
SCHEMBL8209787 0.73 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3HTR6POLB
SCHEMBL8208589 0.72 KMT2A (0.44) SLC6A2SLC6A4SLC6A3HTR6
SCHEMBL8200945 0.72 HTR6 (0.47) HTR6
SCHEMBL8875999 0.71 HTR6 (0.53) SLC6A2SLC6A3HTR6
SCHEMBL7079772 0.71 HTR6 (0.53) SLC6A2SLC6A3HTR6
SCHEMBL8209521 0.70 HTR6 (0.51) HTR6
SCHEMBL8213329 0.70 PTGS1 (0.38) SLC6A2SLC6A4SLC6A3HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012004811-A1 PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2012-01-12 WO disclosed