SCHEMBL16985102

SCHEMBL16985102

c1ccc2c(c1)oc1ccc3c(ccc4oc5ccccc5c43)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.54
MAPT P10636 4/20 0.54
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
GLA P06280 1/20 0.54
CYP3A4 P08684 1/20 0.54
PGAM1 P18669 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
AHR P35869 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CDC14B O60729 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24039791 0.90 MAOA (0.50) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL1635475 0.89 MAOA (0.59) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL19109792 0.89 MAPT (0.47) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL31376230 0.87 TDP1 (0.58) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL29467234 0.83 TDP1 (0.63) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL9779216 0.83 TDP1 (0.63) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL16985934 0.82 PLA2G2A (0.50) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL1635599 0.81 MAPT (0.48) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL9754586 0.81 MAOA (0.52) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL24000691 0.81 AHR (0.49) MAOAMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-11917908-B2 Organic compound, optical device, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-27 US disclosed
US-11917908-B2 Organic compound, optical device, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-02-27 US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-01-06 US disclosed
US-20210193930-A1 ORGANIC COMPOUND, OPTICAL DEVICE, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-06-24 US disclosed
US-20210184130-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, OPTICAL DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-06-17 US disclosed
WO-2020099307-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-22 WO disclosed
US-9447111-B2 Organic thin film transistor, organic semiconductor thin film, and organic semiconductor material FUJIFILM CORPORATION (JP) 2016-09-20 US disclosed
US-9447111-B2 Organic thin film transistor, organic semiconductor thin film, and organic semiconductor material FUJIFILM CORPORATION (JP) 2016-09-20 US disclosed
US-20150218184-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-20150218184-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210193930-A1 ORGANIC COMPOUND, OPTICAL DEVICE, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AOX1, CYP1A1 MAOA 1459/4885MAPT 2280/4885KDM4E 4241/4885
US-20210184130-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, OPTICAL DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE CRY1, NR2E3, GRK1 MAOA 2432/4885MAPT 2321/4885KDM4E 3959/4885
US-11917908-B2 Organic compound, optical device, light-emitting device, light-emitting apparatus, electronic device, and lighting device NR2E3, AOX1, CYP1A1 MAOA 1459/4885MAPT 2280/4885KDM4E 4241/4885
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES ZYX, RER1, AOC2 MAOA 1223/4885MAPT 4261/4885KDM4E 1792/4885
US-20150218184-A1 ORGANIC THIN FILM TRANSISTOR, ORGANIC SEMICONDUCTOR THIN FILM, AND ORGANIC SEMICONDUCTOR MATERIAL POF1B, L1CAM, SLCO2A1 MAOA 1408/4885MAPT 2518/4885KDM4E 3474/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 MAOA 1223/4885MAPT 4261/4885KDM4E 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.