SCHEMBL16985242

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18233455	0.86	NAMPT (0.39)	CA2NAMPTCYP2C9
	SCHEMBL10860405	0.83	CA2 (0.39)	MKNK1CA2CCR2NAMPTHDAC3
	SCHEMBL10558035	0.83	CA2 (0.59)	CA2NAMPT
	SCHEMBL16985241	0.74	CA2 (0.67)	CA2CCR2POLBAKR1B1
	SCHEMBL18233486	0.73	ADAMTS4 (0.40)	NAMPTHDAC3HDAC1HDAC2NCOR2
	Hydrochloric Acid SCHEMBL18223852	0.72	ADAMTS4 (0.39)	NAMPTHDAC3HDAC1HDAC2NCOR2
	SCHEMBL126266	0.72	MAPT (0.51)	MKNK1HDAC3HDAC1HDAC2NCOR2
	SCHEMBL18233494	0.72	NAMPT (0.35)	MKNK1NAMPTHDAC3HDAC1HDAC2
	Hydrochloric Acid SCHEMBL18223643	0.71	NAMPT (0.34)	MKNK1NAMPTHDAC3HDAC1HDAC2
	SCHEMBL16985243	0.70	CA2 (0.51)	MKNK1CA2CCR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.