Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022976 | 0.87 | CA1 (0.46) | NFE2L2MAPK1CA4MEN1GAA | |
| SCHEMBL1093934 | 0.85 | KIF11 (0.50) | KIF11CA4MAOBACHECYP1A2 | |
| SCHEMBL136228 | 0.84 | CA1 (0.46) | NFE2L2MAPK1CA4MEN1GAA | |
| SCHEMBL136230 | 0.79 | NFE2L2 (0.44) | NFE2L2CA4NPC1ABCB1CA1 | |
| SCHEMBL31430103 | 0.79 | NFE2L2 (0.44) | NFE2L2CA4NPC1ABCB1CA1 | |
| SCHEMBL6257499 | 0.77 | CA1 (0.46) | NFE2L2MAPK1CA4MEN1GAA | |
| SCHEMBL7713128 | 0.77 | CA1 (0.46) | NFE2L2MAPK1CA4MEN1GAA | |
| SCHEMBL4660364 | 0.76 | CA1 (0.55) | MAPK1CA4MEN1GAAKMT2A | |
| SCHEMBL2368143 | 0.75 | NR3C2 (0.42) | CA4MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL5583968 | 0.74 | CA1 (0.43) | KIF11NFE2L2MAPK1CA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414790-B2 | Exocyclic nitrogen atom protected nucleoside and method for producing and using the same | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2019-09-17 | — | — | US | disclosed |
| US-20150225442-A1 | EXOCYLIC NITROGEN ATOM PROTECTED NUCLEOSIDE AND METHOD FOR PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414790-B2 | Exocyclic nitrogen atom protected nucleoside and method for producing and using the same | NT5C3B, RNGTT, UMPS | KIF11 3264/4885NFE2L2 3007/4885MAPK1 2529/4885 |
| US-20150225442-A1 | EXOCYLIC NITROGEN ATOM PROTECTED NUCLEOSIDE AND METHOD FOR PRODUCING AND USING THE SAME | NSUN2, RNGTT, NT5C3B | KIF11 2806/4885NFE2L2 2221/4885MAPK1 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.