Sugi Predict

Sugi Predict / Compounds / SCHEMBL136228

SCHEMBL136228

SCHEMBL136228

COc1ccccc1C(OC(c1ccccc1)(c1ccccc1OC)c1ccccc1OC)(c1ccccc1)c1ccccc1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 4/20 0.46
▸ CA2 P00918 4/20 0.46
▸ CA7 P43166 3/20 0.46
▸ CA9 Q16790 3/20 0.46
▸ CA12 O43570 2/20 0.46
▸ CA14 Q9ULX7 2/20 0.46
▸ CA4 P22748 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.39
▸ TP53 P04637 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ ADRA2B P18089 1/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ NR3C2 P08235 1/20 0.38
▸ HTT P42858 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ GAA P10253 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3022976 0.96 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL7713128 0.88 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL6257499 0.88 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL4660364 0.87 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL30886777 0.85 CA1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL5583968 0.85 CA1 (0.43) CA1CA2CA7CA9CA12
Tetraethylene Glycol SCHEMBL2385287 0.84 ALDH1A1 (0.39) CA1CA2CA7CA9CA12
SCHEMBL16987294 0.84 KIF11 (0.43) CA1CA2CA7CA9CA4
SCHEMBL31430103 0.83 NFE2L2 (0.44) CA1CA2CA7CA9CA12
SCHEMBL136230 0.83 NFE2L2 (0.44) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4499655-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES F. Hoffmann-La Roche AG (CH) 2025-02-05 — — EP claimed
WO-2023186842-A1 SYNTHESIS OF ISOMERICALLY PURE POLYOL-BASED PHOSPHORAMIDITES F. HOFFMANN-LA ROCHE AG (CH) 2023-10-05 — — WO claimed
CN-113286803-A S-antigen transport inhibiting oligonucleotide polymers and methods 阿里戈斯治疗公司 2021-08-20 — — CN claimed
EP-3853240-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS Aligos Therapeutics, Inc. (US) 2021-07-28 — — EP claimed
US-20210189392-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2021-06-24 — — US claimed
WO-2021119325-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. (US) 2021-06-17 — — WO claimed
WO-2020119205-A1 RADIOACTIVE FLUORINE-LABELED LAROTRECTINIB COMPOUND AND PREPARATION METHOD THEREFOR 上海健康医学院 2020-06-18 — — WO claimed
US-20200147124-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2020-05-14 — — US claimed
CN-109705124-A A kind of labeled with radioactive fluorine Larotrectinib compound and preparation method thereof 上海健康医学院 2019-05-03 — — CN claimed
WO-2005058246-A2 METHOD FOR PREPARING RADIOLABELED THYMIDINE MOLECULAR TECHNOLOGIES, INC. (US) 2005-06-30 — — WO claimed
US-20050131224-A1 Method for preparing radiolabeled thymidine CTI PET SYSTEMS, INC. 2005-06-16 — — US claimed
US-20030069414-A1 Urea nucleosides as therapeutic and diagnostic agents GILEAD SCIENCES, INC. 2003-04-10 — — US claimed
US-6414137-B1 Selective solvent extraction for the purification of protected nucleosides ALLIEDSIGNAL INC. 2002-07-02 — — US claimed
EP-1140957-A1 SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES AlliedSignal Inc. (US) 2001-10-10 — — EP claimed
US-6143882-A REACTING A NUCLEOSIDE STARTING MATERIAL CONTAINING A LEAVING GROUP WITH A VINYLSTANNE OF DEFINED FORMULA AND CARBON MONOXIDE IN PRESENCE OF A PALLADIUM CATALYST TO FORM AN ENE-ONE INTERMEDIATE, REACTING WITH AN AMINE, AND ISOLATING NEXSTAR PHARMACEUTICALS, INC. (US) 2000-11-07 — — US claimed
WO-2000039138-A1 SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES ALLIEDSIGNAL INC. (US) 2000-07-06 — — WO claimed
WO-1997035868-A9 UREA NUCLEOSIDES AS THERAPEUTIC AND DIAGNOSTIC AGENTS — 1997-12-24 — — WO claimed
WO-1997035868-A1 UREA NUCLEOSIDES AS THERAPEUTIC AND DIAGNOSTIC AGENTS NEXSTAR PHARMACEUTICALS, INC. (US) 1997-10-02 — — WO claimed
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 — — US disclosed
EP-0435150-A2 Amplification capture assay ENZO BIOCHEM, INC. (US) 1991-07-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131224-A1 Method for preparing radiolabeled thymidine TYMP, TYMS, DUT CA1 4668/4885CA2 4858/4885CA7 3394/4885
US-20200147124-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS RNGTT, PHAX, HAVCR2 CA1 3009/4885CA2 3676/4885CA7 3120/4885
US-20030069414-A1 Urea nucleosides as therapeutic and diagnostic agents NUDT1, ADAR, DUT CA1 4340/4885CA2 4540/4885CA7 2927/4885
US-12624391-B2 Cyanine dyes POLL, POLR2E, POLR2H CA1 1460/4885CA2 1892/4885CA7 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.