SCHEMBL1699494

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27921786	0.85	GPR84 (0.43)	GPR84CYP1A2CYP2A6MAPTTP53
	SCHEMBL10271797	0.82	CRHR1 (0.42)	CRHR1KDM4ECYP2C19TNKS
	SCHEMBL243258	0.78	NR4A2 (0.42)	GRM5
	SCHEMBL1699305	0.78	CYP2A6 (0.41)	CYP1A2CYP2A6MAPTALDH1A1HPGD
	SCHEMBL27921801	0.78	GPR84 (0.41)	GPR84CYP1A2CYP2A6MAPTTP53
	SCHEMBL1699379	0.77	GPR84 (0.43)	GPR84CYP1A2CYP2A6MAPTTP53
	SCHEMBL245884	0.76	POLB (0.44)	CYP1A2MAPTTP53CRHR1GRM5
	SCHEMBL23428803	0.76	CYP1A2 (0.45)	CYP1A2CYP2A6PTGS2ALDH1A1HPGD
	SCHEMBL2082932	0.75	ALOX5 (0.55)	GPR84CYP1A2CYP2A6MAPTALOX5
	SCHEMBL1699324	0.72	GPR84 (0.48)	GPR84CYP1A2MAPTALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.