Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699498 | 0.86 | PSEN1 (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL1699290 | 0.75 | L3MBTL1 (0.38) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL10272103 | 0.75 | MAPT (0.39) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL1699312 | 0.75 | ALOX15 (0.39) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1699428 | 0.75 | MAPT (0.39) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL1699478 | 0.70 | CCR2 (0.39) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1699519 | 0.70 | KMT2A (0.38) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL1699600 | 0.68 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL1699658 | 0.66 | ADORA3 (0.42) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1699727 | 0.66 | CCR2 (0.41) | MEN1KMT2AKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588450-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | Gilead Sciences, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003497-A1 | NAPHT- 2 -YLACETIC ACID DERIVATIVES TO TREAT AIDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |