SCHEMBL1699428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10272103	0.92	MAPT (0.39)	MAPTKMT2AALDH1A1LMNAMEN1
	SCHEMBL1699312	0.88	ALOX15 (0.39)	KMT2AALDH1A1LMNAMEN1SMN1; SMN2
	SCHEMBL1699498	0.87	PSEN1 (0.44)	MAPTKMT2AALDH1A1LMNAMEN1
	SCHEMBL1699478	0.83	CCR2 (0.39)	KMT2AALDH1A1LMNAMEN1POLB
	SCHEMBL1699600	0.81	MEN1 (0.40)	MAPTKMT2AALDH1A1MEN1PLG
	SCHEMBL1699290	0.79	L3MBTL1 (0.38)	MAPTKMT2AALDH1A1LMNAMEN1
	SCHEMBL15099653	0.78	TBK1 (0.38)	MAPTALDH1A1LMNASMN1; SMN2RXFP1
	SCHEMBL1699727	0.78	CCR2 (0.41)	MAPTKMT2AMEN1KDM4EMAOB
	SCHEMBL16657255	0.77	ALDH1A1 (0.39)	MAPTALDH1A1LMNAPOLBSMN1; SMN2
	SCHEMBL15093489	0.77	ALDH1A1 (0.39)	MAPTALDH1A1LMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.