SCHEMBL1699290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1699498	0.86	PSEN1 (0.44)	L3MBTL1TDP1ATMPOLBMAOB
	SCHEMBL1699377	0.84	PTPN11 (0.37)	L3MBTL1TDP1ATMMEN1KMT2A
	SCHEMBL1699394	0.82	TOP2A (0.34)	L3MBTL1TDP1ATMPOLBTBXAS1
	SCHEMBL1699519	0.80	KMT2A (0.38)	L3MBTL1TDP1ATMMAOBALOX5
	SCHEMBL1699312	0.79	ALOX15 (0.39)	L3MBTL1MAOBMEN1KMT2AALDH1A1
	SCHEMBL1699428	0.79	MAPT (0.39)	L3MBTL1TDP1POLBMAOBMEN1
	SCHEMBL10272103	0.79	MAPT (0.39)	L3MBTL1TDP1POLBMAOBMEN1
	SCHEMBL1699518	0.75	MEN1 (0.35)	L3MBTL1TDP1POLBTBXAS1MAOB
	SCHEMBL1699478	0.74	CCR2 (0.39)	L3MBTL1POLBMAOBMEN1KMT2A
	SCHEMBL1699303	0.72	TBXAS1 (0.33)	TDP1ATMTBXAS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.