SCHEMBL1699653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1701854	0.90	ALOX15 (0.39)	ALOX15ALDH1A1MAOBKDM4EADORA3
	SCHEMBL1699649	0.85	PTGDR2 (0.43)	ALOX15ALDH1A1HPGDKDM4EMAPT
	SCHEMBL15093746	0.84	ALDH1A1 (0.41)	ALDH1A1ADORA3MAPTLMNA
	SCHEMBL1699637	0.83	ALDH1A1 (0.37)	ALOX15ALDH1A1MAOBHPGDMEN1
	SCHEMBL1699748	0.82	ADORA3 (0.47)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL1699411	0.80	BCL2L1 (0.34)	MEN1KMT2ACASP1ADORA3
	SCHEMBL15093506	0.78	SMN1; SMN2 (0.39)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL1699639	0.77	HTT (0.39)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL15099648	0.77	HTT (0.39)	ALDH1A1HPGDMEN1KMT2AKDM4E
	SCHEMBL16657255	0.76	ALDH1A1 (0.39)	ALDH1A1ADORA3MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.