Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672910 | 0.73 | — | — | |
| SCHEMBL30949855 | 0.72 | — | — | |
| SCHEMBL15915435 | 0.71 | ALOX15 (0.36) | ALOX15LMNA | |
| SCHEMBL27703023 | 0.70 | — | — | |
| SCHEMBL608446 | 0.70 | — | — | |
| SCHEMBL9495241 | 0.68 | ALOX15 (0.42) | ALOX15LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL7704110 | 0.68 | TSHR (0.39) | ALOX15LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL4137634 | 0.67 | ALOX15 (0.40) | ALOX15LMNA | |
| SCHEMBL9472675 | 0.67 | THRB (0.35) | LMNACHRM1CHRM3 | |
| SCHEMBL16290200 | 0.67 | CA2 (0.47) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005980-A1 | NOVEL HETEROBIFUNCTIONAL POLYETHYLENE GLYCOL REAGENTS, THEIR PREPARATION AND USES THEREOF | INTRADIGM CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |