SCHEMBL1701248

SCHEMBL1701248

COCCC(Cl)C(=O)Nc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
ALDH1A1 P00352 4/20 0.53
GAA P10253 2/20 0.53
ATM Q13315 2/20 0.53
LMNA P02545 1/20 0.53
HSP90AA1 P07900 2/20 0.50
GPR55 Q9Y2T6 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
HPGD P15428 2/20 0.49
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
HDAC2 Q92769 2/20 0.46
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
POLB P06746 1/20 0.45
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301643 0.83 CYP1A2 (0.56) MAPTALDH1A1GAAATMLMNA
SCHEMBL8769265 0.82 MAPT (0.57) MAPTALDH1A1GAAATMLMNA
SCHEMBL27709662 0.80 ALDH1A1 (0.54) MAPTALDH1A1GAAATMLMNA
SCHEMBL6545546 0.79 ALDH1A1 (0.61) MAPTALDH1A1GAAATMLMNA
SCHEMBL6901453 0.78 MAPT (0.61) MAPTALDH1A1GAAATMLMNA
SCHEMBL10629250 0.78 ALDH1A1 (0.56) MAPTALDH1A1GAAATMLMNA
SCHEMBL10700016 0.77 MAPT (0.51) MAPTALDH1A1GAAATMLMNA
SCHEMBL8570404 0.76 MAPT (0.58) MAPTALDH1A1GAAATMLMNA
SCHEMBL17548799 0.76 MAPT (0.53) MAPTALDH1A1GAAATMLMNA
SCHEMBL12724392 0.76 ALDH1A1 (0.57) MAPTALDH1A1GAAATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130210630-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (DE) 2013-08-15 US disclosed
WO-2012003441-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (US) 2012-01-05 WO disclosed
WO-2006023409-A1 SOLID POLYMERIC DISPERSANT COMPOSITION FOR WATER-INSOLUBLE ACTIVES ISP INVESTMENTS INC. (US) 2006-03-02 WO disclosed
US-20060039944-A1 Solid polymeric dispersant composition for water-insoluble actives ISP INVESTMENTS INC. 2006-02-23 US disclosed
WO-2004010781-A1 AQUEOUS SUSPENSION AGENT FOR WATER INSOLUBLE COMPOUNDS ISP INVESTMENTS, INC. (US) 2004-02-05 WO disclosed
EP-0505378-B1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC (US) 2001-01-03 EP disclosed
EP-0574492-B1 STABILIZATION OF MICROEMULSIONS USING HYDROPHOBIC ACID BUFFERS ISP INVESTMENTS INC (US) 1999-05-12 EP disclosed
EP-0701398-A4 INERT MATRIX COMPOSITION, PREPARATION THEREOF AND MICROEMULSIFIABLE CONCENTRATE ISP INVESTMENTS INC (US) 1998-01-07 EP disclosed
US-5698211-A AN EMULSION STABILIZER COMPRISING A WATER-INSOLUBLE NONCROSSLINKED N-VINYLLACTAM/ALPHA-OLEFIN COPOLYMER IN A SOLVENT MIXED WITH A WATER-INSOLUBLE AGRICHEMICAL IN SOLVENT CONTAINING A SURFACTANT ISP INVESTMENTS INC. (US) 1997-12-16 US disclosed
US-5672353-A MICROEMULSION STABILIZED WITH WATER INSOLUBLE ALKYL VINYL ETHER/ORGANIC DIACID HALF-ESTER ADDITION COPOLYMER DISSOLVED IN NONAQUEOUS SOLVENT; STORAGE STABILITY ISP INVESTMENTS INC. (US) 1997-09-30 US disclosed
WO-1994028711-A1 INERT MATRIX COMPOSITION, PREPARATION THEREOF AND MICROEMULSIFIABLE CONCENTRATE ISP INVESTMENTS INC. (US) 1994-12-22 WO disclosed
US-5354726-A Hydrophilic and hydrophobic solvents prevent precipitation on extended storage ISP INVESTMENTS INC. (US) 1994-10-11 US disclosed
US-5283229-A A concentrate emulsions comprising an active materials, a surfactant and an amide solvent mixtures to dissolve, dispersing the water insoluble active materials; stability ISP INVESTMENTS INC. (US) 1994-02-01 US disclosed
US-5250499-A Delivery system for agricultural chemicals ISP INVESTMENTS INC. (US) 1993-10-05 US disclosed
WO-1993000809-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1993-01-21 WO disclosed
US-5176736-A Emulsifiable herbicide concentrate ISP INVESTMENTS INC. (US) 1993-01-05 US disclosed
US-5160528-A Stable emulsifiable herbicide concentrates ISP INVESTMENTS INC. (US) 1992-11-03 US disclosed
US-5156666-A Emulsifiable concentrate comprising a pesticide, a surfactant, a hydrophobic solvent and a hydrophilic solvent; storage stability ISP INVESTMENTS INC. (US) 1992-10-20 US disclosed
EP-0505378-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1992-09-30 EP disclosed
WO-1991008665-A1 DELIVERY SYSTEM FOR AGRICULTURAL CHEMICALS ISP INVESTMENTS INC. (US) 1991-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210630-A1 SELF-EMULSIFYING OIL PHOSPHO1, SQLE, ALOX15 MAPT 764/4885ALDH1A1 3915/4885GAA 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.