SCHEMBL30097038

SCHEMBL30097038

CCCCOC(=O)NCc1cc2c(cn1)CCNC2

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
HRH3 Q9Y5N1 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
ACHE P22303 6/20 0.35
TGFBR1 P36897 1/20 0.35
HTR2B P41595 1/20 0.34
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30097054 0.81 L3MBTL1 (0.38) L3MBTL1HTR2B
SCHEMBL30097053 0.80 MAOA (0.36) L3MBTL1RAB9A
SCHEMBL23705922 0.79 HTR2B (0.45) HTR2B
SCHEMBL17017128 0.74 L3MBTL1 (0.46) L3MBTL1ACHETGFBR1RAB9A
SCHEMBL30097048 0.72 TP53 (0.41)
SCHEMBL17017926 0.71 L3MBTL1 (0.46) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL30097047 0.70 FAAH (0.44) L3MBTL1TGFBR1RAB9ANPC1SMN1; SMN2
SCHEMBL22366449 0.69 L3MBTL1 (0.47) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL30097018 0.69 ATM (0.44) L3MBTL1TGFBR1RAB9ANPC1SMN1; SMN2
SCHEMBL30097049 0.69 MAPKAPK2 (0.42) L3MBTL1TGFBR1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4096667-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 EP disclosed