Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574376 | 0.82 | GRM2 (0.49) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL17022722 | 0.80 | LMNA (0.56) | TSHR | |
| SCHEMBL15103577 | 0.77 | FOLH1 (0.40) | MAPTTSHR | |
| SCHEMBL29201074 | 0.76 | TDP1 (0.53) | GRM2CYP3A4TSHR | |
| SCHEMBL6496581 | 0.75 | GRM2 (0.49) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL14486238 | 0.75 | GRM2 (0.49) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL29118765 | 0.73 | TAAR1 (0.44) | GRM2MAOB | |
| SCHEMBL7634585 | 0.72 | GRM2 (0.46) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL2204622 | 0.72 | CTSV (0.44) | MAOBMAPTCYP2C19 | |
| SCHEMBL7628338 | 0.72 | GRM2 (0.53) | GRM2SLC6A2SLC6A4SLC6A3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910540-B1 | NOVEL RUTHENIUM COMPLEX AND METHOD FOR PREPARING METHANOL AND DIOL | SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) | 2021-09-15 | — | — | EP | disclosed |
| US-9434665-B2 | Ruthenium complex and method for preparing methanol and diol | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-09-06 | — | — | US | disclosed |
| US-20160060195-A1 | NOVEL RUTHENIUM COMPLEX AND METHOD FOR PREPARING METHANOL AND DIOL | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-03 | — | — | US | disclosed |
| EP-2910540-A1 | NOVEL RUTHENIUM COMPLEX AND METHOD FOR PREPARING METHANOL AND DIOL | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2015-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060195-A1 | NOVEL RUTHENIUM COMPLEX AND METHOD FOR PREPARING METHANOL AND DIOL | CCNY, DPY30, RUVBL1 | GRM2 2628/4885SLC6A2 4660/4885SLC6A4 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.