SCHEMBL2204622

SCHEMBL2204622

O=C1OCCC(OCc2ccccc2)O1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
CTSC P53634 1/20 0.44
CTSF Q9UBX1 1/20 0.44
PSEN1 P49768 4/20 0.40
PSEN2 P49810 4/20 0.40
APH1B Q8WW43 4/20 0.40
NCSTN Q92542 4/20 0.40
APH1A Q96BI3 4/20 0.40
PSENEN Q9NZ42 4/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CCKBR P32239 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28117882 0.84 MAPT (0.43) CTSVCTSLCTSBCTSSCTSK
SCHEMBL8721815 0.78 CTSV (0.46) CTSVCTSLCTSBCTSSCTSK
SCHEMBL19041070 0.77 SIGMAR1 (0.42) CTSVCTSLCTSBCTSSCTSK
SCHEMBL17022722 0.76 LMNA (0.56) CTSLCTSBCTSKKMT2AMEN1
SCHEMBL2571382 0.74 TSHR (0.43) CTSVCTSLCTSBCTSSCTSK
SCHEMBL24190480 0.74 CYP1A2 (0.46) CTSVCTSLCTSBCTSSCTSK
SCHEMBL29015434 0.74 CYP1A2 (0.46) CTSVCTSLCTSBCTSSCTSK
SCHEMBL17022698 0.72 GRM2 (0.46) MAPTCYP2C19MAOB
SCHEMBL9171466 0.72 TSHR (0.44) CTSVCTSLCTSBCTSSCTSK
SCHEMBL27559526 0.71 PSEN1 (0.41) CTSVCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110165244-A1 BIORESPONSIVE POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS ALLVIVO VASCULAR, INC. (US) 2011-07-07 US claimed
US-10400064-B2 Glycerol-based polycarbonates TRUSTEES OF BOSTON UNIVERSITY (US) 2019-09-03 US disclosed
US-20170369643-A1 GLYCEROL-BASED POLYCARBONATES TRUSTEES OF BOSTON UNIVERSITY (US) 2017-12-28 US disclosed
WO-2016086118-A1 GLYCEROL-BASED POLYCARBONATES TRUSTEES OF BOSTON UNIVERSITY (US) 2016-06-02 WO disclosed
US-20110165244-A1 BIORESPONSIVE POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS ALLVIVO VASCULAR, INC. (US) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10400064-B2 Glycerol-based polycarbonates GK, AGPAT5, PC CTSV 3919/4885CTSL 4487/4885CTSB 3344/4885
US-20110165244-A1 BIORESPONSIVE POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS BMP2, BMP1, PGF CTSV 800/4885CTSL 158/4885CTSB 302/4885
US-20170369643-A1 GLYCEROL-BASED POLYCARBONATES GK, PGK1, PARG CTSV 2746/4885CTSL 4245/4885CTSB 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.