Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486238 | 1.00 | GRM2 (0.49) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL7634585 | 0.89 | GRM2 (0.46) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL5688628 | 0.88 | GRM2 (0.45) | GRM2SLC6A2SLC6A4SLC6A3F2 | |
| SCHEMBL25253641 | 0.82 | CYP26A1 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL9452532 | 0.82 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18973360 | 0.80 | ESR1 (0.48) | — | |
| SCHEMBL32665727 | 0.80 | ESR1 (0.48) | — | |
| SCHEMBL19760193 | 0.80 | ALDH1A1 (0.43) | CYP1A2MAPT | |
| SCHEMBL7286647 | 0.80 | CYP1A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL7628338 | 0.79 | GRM2 (0.53) | GRM2SLC6A2SLC6A4SLC6A3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180273503-A1 | NOVEL ANGIOTENSIN CONVERTING ENZYME INHIBITOR | RIKEN (JP) | 2018-09-27 | — | — | US | disclosed |
| US-10059650-B2 | Systems and methods for the depolymerization of a biopolymer | YALE UNIVERSITY (US) | 2018-08-28 | — | — | US | disclosed |
| US-20180000761-A1 | Methods for Making Catechin Derivatives | UNIVERSITY OF SOUTH FLORIDA (US) | 2018-01-04 | — | — | US | disclosed |
| US-20160130202-A1 | Systems and Methods for the Depolymerization of a Biopolymer | YALE UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2005-05-26 | — | — | US | disclosed |
| CN-1128819-C | Water soluble polymers and their use in cosmetic formulations | BASF AG (DE) | 2003-11-26 | — | — | CN | disclosed |
| EP-1347950-A1 | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND OF ITS HIGHER HOMOLOGUE AS LIGANDS OF GAMMA-HYDROXYBUTYRATE (GHB) RECEPTORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES | Université Louis Pasteur, (Etablissement public à caractère scientifique, culturel et professionnel) (FR) | 2003-10-01 | — | — | EP | disclosed |
| US-6458348-B1 | Use of water-soluble polymers as biocides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| WO-2002042250-A1 | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND OF ITS HIGHER HOMOLOGUE AS LIGANDS OF η-HYDROXYBUTYRATE (GHB) RECEPTORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2002-05-30 | — | — | WO | disclosed |
| EP-0915915-B1 | WATER SOLUBLE POLYMERS AND THEIR USE IN COSMETIC FORMULATIONS | BASF AG (DE) | 2001-10-31 | — | — | EP | disclosed |
| US-6271327-B1 | HYDROXYALKYLACRYLIC AMIDES AND DIHYDROXYALKYLACRYLIC IMIDE POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-1014788-A1 | USE OF WATER-SOLUBLE POLYMERS AS BIOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-05 | — | — | EP | disclosed |
| CN-1232473-A | Water-soluble polymers and their use in cosmetic formulations | BASF AG (DE) | 1999-10-20 | — | — | CN | disclosed |
| EP-0915915-A1 | WATER SOLUBLE POLYMERS AND THEIR USE IN COSMETIC FORMULATIONS | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999012420-A1 | USE OF WATER-SOLUBLE POLYMERS AS BIOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| WO-1998004596-A1 | WATER SOLUBLE POLYMERS AND THEIR USE IN COSMETIC FORMULATIONS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | GABRB1, GABRA1, GABRA5 | GRM2 97/4885SLC6A2 804/4885SLC6A4 650/4885 |
| US-20180273503-A1 | NOVEL ANGIOTENSIN CONVERTING ENZYME INHIBITOR | ACE, ACE2, REN | GRM2 3757/4885SLC6A2 647/4885SLC6A4 1976/4885 |
| US-20180000761-A1 | Methods for Making Catechin Derivatives | EP300, ADH1C, ADH1A | GRM2 4300/4885SLC6A2 372/4885SLC6A4 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.