SCHEMBL1702308

SCHEMBL1702308

CN1CCNCCNCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.43
MAPT P10636 1/20 0.43
PDE4A P27815 1/20 0.43
KDR P35968 1/20 0.43
PHGDH O43175 1/20 0.40
CXCR4 P61073 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.35
POLB P06746 1/20 0.35
ADRB1 P08588 3/20 0.33
SOS1 Q07889 1/20 0.33
SOS2 Q07890 1/20 0.33
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
CHKA P35790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HTR3E A5X5Y0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL3658609 1.00 HIF1A (0.43) HIF1AMAPTPDE4AKDRPHGDH
SCHEMBL3111675 1.00 HIF1A (0.43) HIF1AMAPTPDE4AKDRPHGDH
SCHEMBL8200625 1.00 HIF1A (0.43) HIF1AMAPTPDE4AKDRPHGDH
SCHEMBL16289999 0.97 PHGDH (0.43) HIF1AMAPTPDE4AKDRPHGDH
Methylpiperazine SCHEMBL54849 0.96
Methylpiperazine SCHEMBL12678256 0.96
SCHEMBL154155 0.96 PHGDH (0.41) HIF1AMAPTPDE4AKDRPHGDH
Methylpiperazine SCHEMBL12678259 0.96
Methylpiperazine SCHEMBL1363 0.96
Methylpiperazine SCHEMBL12678252 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117421-A1 PAINTS CONTAINING DRIERS BASED ON VANADIUM COMPOUNDS BEARING VARIOUS ACID ANIONS BORCHERS GMBH (DE) 2023-06-29 WO claimed
US-20180369428-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) 2018-12-27 US claimed
EP-3281643-A2 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE Kyungpook National University Industry-Academic Cooperation Foundation (KR) 2018-02-14 EP claimed
US-20050131186-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom PENNSYLVANIA, UNIVERSITY OF 2005-06-16 US claimed
WO-2023117421-A1 PAINTS CONTAINING DRIERS BASED ON VANADIUM COMPOUNDS BEARING VARIOUS ACID ANIONS BORCHERS GMBH (DE) 2023-06-29 WO disclosed
WO-2023107648-A2 SYNTHESIS OF ESTER, CARBONATE, AND CARBAMATE-DERIVED NOVEL BIODEGRADABLE IONIZABLE LIPIDS FROM METHYL RICINOLEATE OR METHYL 12-HYDROXYSTEARATE AND ITS APPLICATIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-15 WO disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed
CN-114026211-A Machine dishwashing detergent containing ethoxylated glycerides 科莱恩国际有限公司 2022-02-08 CN disclosed
US-10889554-B2 Excimer forming compounds THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-01-12 US disclosed
WO-2020236084-A1 MOLECULAR DESIGN OF NEW ANTIBIOTICS AND ANTIBIOTIC ADJUVANTS AGAINST MCR STRAINS SINGAPORE HEALTH SERVICES PTE LTD (SG) 2020-11-26 WO disclosed
WO-2020102820-A1 COMPOUNDS FOR USE AS IRON (III) MRI CONTRAST AGENTS CONTAINING ANIONIC PENDENTS AND ANCILLARY GROUPS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2020-05-22 WO disclosed
EP-0932659-A2 PROCESS FOR MAKING A HIGH DENSITY DETERGENT COMPOSITION VIA POST DRYING MIXING/DENSIFICATION THE PROCTER & GAMBLE COMPANY (US) 1999-08-04 EP disclosed
EP-0931135-A1 LOW FOAMING AUTOMATIC DISHWASHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-07-28 EP disclosed
WO-1999006522-A1 DETERGENT TABLET THE PROCTER & GAMBLE COMPANY (US) 1999-02-11 WO disclosed
WO-1998016618-A2 PROCESS FOR MAKING A HIGH DENSITY DETERGENT COMPOSITION VIA POST DRYING MIXING/DENSIFICATION THE PROCTER & GAMBLE COMPANY (US) 1998-04-23 WO disclosed
WO-1998011190-A1 LOW FOAMING AUTOMATIC DISHWASHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-03-19 WO disclosed
EP-0796317-A1 AUTOMATIC DISHWASHING COMPOSITION CONTAINING PARTICLES OF DIACYL PEROXIDES THE PROCTER & GAMBLE COMPANY (US) 1997-09-24 EP disclosed
WO-1996017921-A1 AUTOMATIC DISHWASHING COMPOSITION CONTAINING PARTICLES OF DIACYL PEROXIDES THE PROCTER & GAMBLE COMPANY (US) 1996-06-13 WO disclosed
WO-1994004485-A1 LIGANDS FOR Ga-68 PET HEART APPLICATIONS MALLINCKRODT MEDICAL, INC. (US) 1994-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180369428-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE TST, CTH, CBS HIF1A 450/4885MAPT 3502/4885PDE4A 4765/4885
US-10889554-B2 Excimer forming compounds PHAX, RNMT, POLM HIF1A 4361/4885MAPT 4176/4885PDE4A 3904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.