Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023221 | 0.89 | L3MBTL1 (0.47) | LMNASMN1; SMN2RAB9AALDH1A1TSHR | |
| SCHEMBL17023229 | 0.85 | L3MBTL1 (0.48) | LMNASMN1; SMN2HPGDRAB9AALDH1A1 | |
| SCHEMBL17023231 | 0.85 | LMNA (0.46) | LMNASMN1; SMN2RAB9AALDH1A1TSHR | |
| SCHEMBL1874546 | 0.85 | LMNA (0.59) | LMNAMAPK10SMN1; SMN2POLBHPGD | |
| SCHEMBL17023227 | 0.84 | L3MBTL1 (0.45) | LMNASMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL17023233 | 0.84 | KMT2A (0.46) | LMNASMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL17023215 | 0.83 | KDM4E (0.49) | SMN1; SMN2POLBHPGDRAB9AALDH1A1 | |
| SCHEMBL17023210 | 0.83 | USP2 (0.41) | LMNASMN1; SMN2RAB9AALDH1A1TSHR | |
| SCHEMBL17023232 | 0.82 | NPC1 (0.47) | LMNASMN1; SMN2POLBRAB9AALDH1A1 | |
| SCHEMBL17023228 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2POLBRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |