Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023221 | 0.86 | L3MBTL1 (0.47) | KDM4ESMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL17023223 | 0.83 | GAA (0.48) | SMN1; SMN2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL17023229 | 0.83 | L3MBTL1 (0.48) | KDM4ESMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL17023214 | 0.83 | ADORA3 (0.40) | KDM4ESMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL17023217 | 0.83 | LMNA (0.52) | KDM4ESMN1; SMN2HPGDPOLBRAB9A | |
| SCHEMBL17023231 | 0.83 | LMNA (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL17023233 | 0.82 | KMT2A (0.46) | SMN1; SMN2HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL17023227 | 0.82 | L3MBTL1 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1878308 | 0.82 | KDM4E (0.57) | KDM4ESMN1; SMN2HPGDPOLBRAB9A | |
| SCHEMBL17023213 | 0.82 | ADORA3 (0.35) | KDM4ESMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |