SCHEMBL17025705

SCHEMBL17025705

CCCCC(CCCC)C(N)(N)CCCC

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.37
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
DNM1 Q05193 2/20 0.35
OPRM1 P35372 1/20 0.33
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
SMPD1 P17405 2/20 0.30
TSHR P16473 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27647583 0.91 ALDH1A1 (0.38) FDPSALDH1A1TDP1DNM1OPRM1
SCHEMBL27761566 0.89 FDPS (0.46) FDPSDNM1OPRM1SMPD1
SCHEMBL28589370 0.88 FDPS (0.34) FDPSCA2CA1
SCHEMBL29159276 0.86 FDPS (0.34) FDPSALDH1A1TDP1DNM1OPRM1
SCHEMBL302193 0.80 FDPS (0.37) FDPSALDH1A1TDP1DNM1OPRM1
SCHEMBL6021613 0.79 DNM1 (0.44) FDPSALDH1A1DNM1SMPD1TSHR
Hydrochloric Acid SCHEMBL5088126 0.78 FDPS (0.35) FDPSALDH1A1TDP1DNM1OPRM1
SCHEMBL22027682 0.78 TSHR (0.38) FDPSALDH1A1TDP1DNM1OPRM1
SCHEMBL15797814 0.78 ALDH1A1 (0.39) FDPSALDH1A1TDP1DNM1OPRM1
Iodide SCHEMBL5091363 0.78 FDPS (0.35) FDPSALDH1A1TDP1DNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158476-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2024-05-16 US claimed
CN-111601626-B Medical device with integrated biosensor 生物克瑞德公司 2022-05-06 CN claimed
US-20210380420-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2021-12-09 US claimed
US-20210220523-A1 NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2021-07-22 US claimed
EP-3826628-A1 NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS University of Georgia Research Foundation, Inc. (US) 2021-06-02 EP claimed
EP-3823683-A1 ROBUST NITRIC OXIDE-RELEASING POLYMERS AND ARTICLES AND METHODS OF MAKING AND USES THEREOF University of Georgia Research Foundation, Inc. (US) 2021-05-26 EP claimed
CN-111601626-A Medical device with integrated biosensor 生物克瑞德公司 2020-08-28 CN claimed
WO-2020041617-A1 NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2020-02-27 WO claimed
WO-2020018488-A1 ROBUST NITRIC OXIDE-RELEASING POLYMERS AND ARTICLES AND METHODS OF MAKING AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2020-01-23 WO claimed
US-20190039910-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2019-02-07 US claimed
CN-104927348-A Antibacterial and anticoagulant polymer material, preparation method and application thereof UNIV BEIJING CHEMICAL 2015-09-23 CN claimed
WO-2025080553-A1 NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2025-04-17 WO disclosed
US-20240158476-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2024-05-16 US disclosed
US-20240139385-A1 PHOTOTRIGGERABLE NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF UNIV GEORGIA (US) 2024-05-02 US disclosed
US-20240131231-A1 NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF NATIONAL INSTITUTES OF HEALTH 2024-04-25 US disclosed
WO-2020018488-A1 ROBUST NITRIC OXIDE-RELEASING POLYMERS AND ARTICLES AND METHODS OF MAKING AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2020-01-23 WO disclosed
US-20190039910-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2019-02-07 US disclosed
US-9566372-B2 Sustained nitric oxide release coating using diazeniumdiolate-doped polymer matrix with ester capped poly(lactic-co-glycolic acid) additive THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2017-02-14 US disclosed
CN-104927348-A Antibacterial and anticoagulant polymer material, preparation method and application thereof UNIV BEIJING CHEMICAL 2015-09-23 CN disclosed
US-20150238662-A1 SUSTAINED NITRIC OXIDE RELEASE COATING USING DIAZENIUMDIOLATE-DOPED POLYMER MATRIX WITH ESTER CAPPED POLY(LACTIC-CO-GLYCOLIC ACID) ADDITIVE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139385-A1 PHOTOTRIGGERABLE NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF NOS2, NOS1, NOS3 FDPS 199/4885ALDH1A1 2519/4885TDP1 1037/4885
US-20240131231-A1 NITRIC OXIDE-RELEASING COMPOSITIONS AND APPLICATIONS THEREOF NOS2, NOS1, NOS3 FDPS 377/4885ALDH1A1 2686/4885TDP1 1189/4885
US-20210220523-A1 NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS NOS2, NOS1, NOS3 FDPS 2153/4885ALDH1A1 2724/4885TDP1 942/4885
US-20240158476-A1 MESOPOROUS NITRIC OXIDE-RELEASING SILICA PARTICLES, METHODS OF MAKING, AND USES THEREOF NOS1, NOS2, DDO FDPS 452/4885ALDH1A1 2327/4885TDP1 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.