Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703192 | 0.87 | RET (0.35) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL30689020 | 0.87 | RET (0.35) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL1906187 | 0.79 | GPR3 (0.41) | GPR3KDM4ELMNATP53CHRM2 | |
| SCHEMBL7545621 | 0.79 | GPR3 (0.33) | GPR3KDM4ELMNATP53CHRM2 | |
| SCHEMBL28916605 | 0.77 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL4651581 | 0.76 | RET (0.35) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL970789 | 0.76 | BRD4 (0.35) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL30689015 | 0.76 | BRD4 (0.35) | KDM4ELMNATP53CHRM2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8534599 | 0.76 | GPR3 (0.32) | GPR3KDM4ELMNATP53CHRM2 | |
| SCHEMBL9148551 | 0.75 | RET (0.34) | KDM4ELMNATP53CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428716-B | Catalyst system, olefin polymerization catalyst component comprising at least an internal electron donor compound, and methods of making and using the same | 格雷斯公司 | 2021-05-11 | — | — | CN | claimed |
| CN-109134720-B | External electron donors for olefin polymerization | 印度石油有限公司 | 2021-03-05 | — | — | CN | claimed |
| US-20250109220-A1 | Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound | W. R. GRACE & CO.-CONN. | 2025-04-03 | — | — | US | disclosed |
| US-12240925-B2 | Process for preparing solid catalyst components for olefin polymerization | W. R. GRACE & CO.- CONN. (US) | 2025-03-04 | — | — | US | disclosed |
| EP-4473023-A1 | OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND | W.R. GRACE & CO.-CONN. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20240174776-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2024-05-30 | — | — | US | disclosed |
| US-11891460-B2 | Activated catalyst components for olefin polymerization | W. R. GRACE & CO.-CONN. (US) | 2024-02-06 | — | — | US | disclosed |
| EP-4308615-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W. R. Grace & Co.-Conn (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023147021-A1 | OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND | W.R. GRACE & CO.-CONN. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-2785752-B1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BRASKEM AMERICA INC (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11634520-B2 | Catalyst components for propylene polymerization | W.R. GRACE & CO.-CONN. (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2002016444-A2 | (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2002-02-28 | — | — | WO | disclosed |
| US-6350828-B1 | Polypropylene resin composition and use thereof | GRAND POLYMER CO LTD (JP) | 2002-02-26 | — | — | US | disclosed |
| US-6306973-B1 | Polypropylene block-copolymer resin and process for producing it | GRAND POLYMER CO. LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1026184-A1 | Polypropylene block-copolymer resin and process for producing it | Grand Polymer Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0942013-A1 | POLYPROPYLENE RESIN COMPOSITION AND USE THEREOF | Grand Polymer Co., Ltd. (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5438110-A | Homopolymerizing or copolymerizing olefins in presence of catalyst formed from solid component containing titanium, magnesium, halogen, electron donor, organoaluminum compound, organosilicon compound having cyclopentyl group | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0350170-B1 | Process for polymerising olefins and polymerisation catalyst therefor | MITSUI PETROCHEMICAL IND (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-4990479-A | Coordination catalysts | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0350170-A2 | Process for polymerising olefins and polymerisation catalyst therefor | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240925-B2 | Process for preparing solid catalyst components for olefin polymerization | POF1B, PPOX, OGFOD1 | GPR3 3993/4885KDM4E 1433/4885LMNA 4650/4885 |
| US-11634520-B2 | Catalyst components for propylene polymerization | PPIP5K2, PHPT1, PPOX | GPR3 4269/4885KDM4E 1366/4885LMNA 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.