Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 7/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19185358 | 0.81 | IRAK4 (0.41) | IRAK4TRPA1PRKD3MAP4K4PAK4 | |
| SCHEMBL19185239 | 0.77 | MAP3K7 (0.54) | IRAK4ROCK2ROCK1LRRK2HSP90AB1 | |
| SCHEMBL9967152 | 0.76 | AKT1 (0.46) | AKT1IRAK4TRPA1LIMK1ROCK2 | |
| SCHEMBL19185382 | 0.75 | MAP3K7 (0.41) | — | |
| SCHEMBL10259826 | 0.75 | AKT1 (0.45) | AKT1IRAK4TRPA1LIMK1ROCK2 | |
| SCHEMBL20171693 | 0.73 | CHEK1 (0.47) | AKT1IRAK4TRPA1LIMK1ROCK2 | |
| SCHEMBL357993 | 0.73 | CHEK1 (0.61) | AKT1IRAK4TRPA1LIMK1ROCK2 | |
| SCHEMBL1804027 | 0.73 | AKT1 (0.44) | AKT1IRAK4TRPA1LIMK1ROCK2 | |
| SCHEMBL26777937 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL21392347 | 0.70 | EGFR (0.47) | IRAK4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
| US-20190292189-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC | 2019-09-26 | — | — | US | disclosed |
| US-9511070-B2 | Heterocyclyl carboxamides for treating viral diseases | NOVADRUG, LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150238489-A1 | HETEROCYCLYL CARBOXAMIDES FOR TREATING VIRAL DISEASES | NOVADRUG, LLC | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | AKT1 2136/4885IRAK4 1827/4885TRPA1 1604/4885 |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | AKT1 2136/4885IRAK4 1827/4885TRPA1 1604/4885 |
| US-11820766-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | AKT1 2136/4885IRAK4 1827/4885TRPA1 1604/4885 |
| US-20150238489-A1 | HETEROCYCLYL CARBOXAMIDES FOR TREATING VIRAL DISEASES | SARS1, PYCARD, BRD1 | AKT1 4352/4885IRAK4 1851/4885TRPA1 1091/4885 |
| US-20190292189-A1 | LIM KINASE INHIBITORS | LIMK1, LIMK2, LIMA1 | AKT1 110/4885IRAK4 402/4885TRPA1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.