Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423344 | 0.89 | THRB (0.49) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL11650141 | 0.89 | THRB (0.49) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL18492364 | 0.89 | MAPK1 (0.49) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL17034357 | 0.87 | THRB (0.40) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL17034350 | 0.85 | TGM2 (0.43) | THRBSMN1; SMN2L3MBTL1 | |
| SCHEMBL17034292 | 0.85 | LMNA (0.42) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL17034359 | 0.84 | TGM2 (0.46) | THRBTSHR | |
| SCHEMBL18492271 | 0.83 | ADRB2 (0.53) | THRBADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL13423351 | 0.83 | LMNA (0.46) | THRBADRB2ADRB1ADRB3MAPK1 | |
| SCHEMBL19456757 | 0.83 | THRB (0.43) | THRBADRB2ADRB1ADRB3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |