Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047713 | 0.82 | MEN1 (0.40) | ALDH1A1GAA | |
| SCHEMBL17047688 | 0.80 | HTR7 (0.35) | HTR7AADATTRPA1DAOPDE7A | |
| SCHEMBL17047646 | 0.76 | FAAH (0.42) | ALDH1A1GAA | |
| SCHEMBL17047801 | 0.75 | RXFP1 (0.43) | HTR7ALDH1A1 | |
| SCHEMBL17047790 | 0.74 | RXFP1 (0.38) | ALDH1A1GAA | |
| SCHEMBL20320588 | 0.64 | — | — | |
| SCHEMBL20331352 | 0.61 | — | — | |
| SCHEMBL20313856 | 0.61 | — | — | |
| SCHEMBL21534348 | 0.61 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL20330657 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110808-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| US-9751867-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-3110808-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-22 | — | — | US | disclosed |
| WO-2015128321-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | GHDC, GAK, EIF4G2 | HTR7 3134/4885AADAT 3085/4885TRPA1 4699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.