Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048875 | 0.69 | GPR35 (0.36) | — | |
| SCHEMBL3700951 | 0.69 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL5164396 | 0.65 | ACHE (0.42) | — | |
| SCHEMBL17048878 | 0.64 | — | — | |
| SCHEMBL17048826 | 0.63 | HSP90AA1 (0.38) | — | |
| SCHEMBL17048823 | 0.62 | HSD17B10 (0.32) | — | |
| SCHEMBL458881 | 0.62 | MEN1 (0.30) | — | |
| SCHEMBL12597644 | 0.62 | ALDH1A1 (0.46) | — | |
| SCHEMBL22749806 | 0.62 | GSR (0.31) | — | |
| SCHEMBL17048849 | 0.62 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |