Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 6/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706305 | 0.94 | RNASE1 (0.38) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL9755145 | 0.94 | RNASE1 (0.38) | RNASE1TK1TOP2ATK2 | |
| Succinic Acid SCHEMBL1705784 | 0.90 | RNASE1 (0.37) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL1705935 | 0.90 | RNASE1 (0.35) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL7640415 | 0.88 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL1727535 | 0.87 | RNASE1 (0.40) | RNASE1TK1TK2 | |
| SCHEMBL8370048 | 0.86 | RNASE1 (0.38) | RNASE1TK1TK2 | |
| SCHEMBL7863893 | 0.85 | RNASE1 (0.37) | RNASE1TK1TOP2ATK2 | |
| SCHEMBL20636773 | 0.85 | LMNA (0.38) | RNASE1TOP2A | |
| SCHEMBL3612838 | 0.85 | TK1 (0.38) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700642-A | HYBRIDIZING PRIMER WITH COMPLEMENTARY TARGET NUCLEIC ACID, ENZYMATICALLY EXTENDING PRIMER TO GENERATE POLYNUCLEOTIDE MIXTURE, IMMOBILIZATION, CLEAVING TO RELEASE EXTENSION SEGMENT AND MEASUREMENT BY MASS SPECTROMETRY | SRI INTERNATIONAL (US) | 1997-12-23 | — | — | US | disclosed |